Co-speciation in bedbug Wolbachia parallel the pattern in nematode hosts
Co-speciation in bedbug Wolbachia parallel the pattern in nematode hosts
复制标题
DOI：
10.1038/s41598-018-25545-y
复制
发表时间：
2018-06-11
影响因子：
4.6
通讯作者：
Reinhardt, Klaus
中科院分区：
文献类型：
--
作者：
Balvin, Ondrej;Roth, Steffen;Reinhardt, Klaus
沃尔巴克氏菌是垂直传播的细胞内内共生菌，与两个主要宿主分类群相关，它们表现出截然不同的共生模式。在一些丝虫线虫类群中，沃尔巴克氏体对宿主绝对有益，它们表现出完全的种内和种间流行以及与宿主的共系统发育。在节肢动物中，沃尔巴克氏体通常是寄生的。如果发生有益的影响，它们可能是兼性的或必然的，与宿主繁殖有关。在节肢动物中，沃尔巴克氏体的流行率在类群内部和类群之间存在差异，并且尚无已知的共物种事件。然而，最近发现一种节肢动物——常见的臭虫温带臭虫（Cimex lectularius）依赖于沃尔巴克氏体提供的生物素和核黄素，这代表了沃尔巴克氏体为节肢动物宿主提供营养和专性益处的独特案例，甚至可能以互惠互利的方式。利用可能具有功能的生物素基因拷贝的存在，我们的研究表明，在 Cimex 和 Paracimex 属的 15 个物种中，至少有 10 个物种保持着专性关系。其余五个物种也含有沃尔巴克氏体，这是第一个已知的高等节肢动物类群中沃尔巴克氏体 100% 流行的案例。此外，我们还展示了沃尔巴克氏体与其臭虫宿主之间预测的共同分支发生，这也是第一个描述的节肢动物中沃尔巴克氏体共物种形成的案例。
Wolbachia bacteria, vertically transmitted intracellular endosymbionts, are associated with two major host taxa in which they show strikingly different symbiotic modes. In some taxa of filarial nematodes, where Wolbachia are strictly obligately beneficial to the host, they show complete within-and amongspecies prevalence as well as co-phylogeny with their hosts. In arthropods, Wolbachia usually are parasitic; if beneficial effects occurs, they can be facultative or obligate, related to host reproduction. In arthropods, the prevalence of Wolbachia varies within and among taxa, and no co-speciation events are known. However, one arthropod species, the common bedbug Cimex lectularius was recently found to be dependent on the provision of biotin and riboflavin by Wolbachia, representing a unique case of Wolbachia providing nutritional and obligate benefits to an arthropod host, perhaps even in a mutualistic manner. Using the presence of presumably functional biotin gene copies, our study demonstrates that the obligate relationship is maintained at least in 10 out of 15 species of the genera Cimex and Paracimex. The remaining five species harboured Wolbachia as well, demonstrating the first known case of 100% prevalence of Wolbachia among higher arthropod taxa. Moreover, we show the predicted co-cladogenesis between Wolbachia and their bedbug hosts, also as the first described case of Wolbachia co-speciation in arthropods.