Some characteristics of a factor stimulating skin epithelial cell growth in vitro.
Some characteristics of a factor stimulating skin epithelial cell growth in vitro.
复制标题
DOI：
10.1016/0014-4827(73)90446-1
复制
发表时间：
1973-06
影响因子：
3.7
通讯作者：
S. Melbye;M. Karasek
中科院分区：
文献类型：
--
作者：
S. Melbye;M. Karasek
Growth of rabbit skin epithelial cells on a collagen gel is markedly enhanced by a soluble factor synthesized in a chemically defined minimal growth medium by fibroblasts of dermal origin. In the presence of this factor, the incorporation of thymidine and phosphate into skin epithelial cells is stimulated, and survival time of skin epithelial cells is prolonged. The growth factor is small (mol.wt < 1 000 D) and is not sensitive to lyophilization, heating, repeated freezing and thawing or the action of degradative enzymes RNAse, DNAse, trypsin and pronase. The chemical properties of the growth factor are not those expected of a free amino acid, peptide, non-polar lipid or nucleic acid.
