Molybdenum requirements in low-birth-weight infants receiving parenteral and enteral nutrition.

Molybdenum requirements in low-birth-weight infants receiving parenteral and enteral nutrition.
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接受肠外和肠内营养的低出生体重婴儿的钼需求。

DOI:
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发表时间:
1999
期刊:
影响因子:
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通讯作者:
W. Andrews
W. Andrews
中科院分区:
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文献类型:
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作者:
J. Friel;A. Macdonald;C. Mercer;Suresh L. Belkhode;Geoff Downton;P. Kwa;K. Aziz;W. Andrews

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背景:钼(Mo)是三种酶系统所必需的微量元素,但目前尚无婴儿缺钼的报道。低出生体重儿(LBW)可能存在钼缺乏的风险,因为他们出生在获得足够的钼储备之前,他们生长迅速,需要增加摄入量,他们经常接受补充的肠外营养(SPN)和不补充钼的完全肠外营养(TPN)。方法:调查低出生体重儿(n=16;出生体重1336±351g;胎龄29.8±2.5周;M±SD)TPN前(基线,n=16)、TPN(n=9,收集=19)、SPN(n=13,收集=17)、配方奶或母乳喂养(FOF,n=16,收集=16)前、中、后饲料、尿液和粪便的钼需要量。结果:采集婴儿体重分别为1.3±0.3g、1.27±0.4g、1.4±0.3g、1.7±0.5g。钼摄入量。
Background: Molybdenum (Mo) is an essential trace element required by three enzymatic systems, yet there are no reports of Mo deficiency in infants. Low-birth-weight infants (LBW) might be at risk for Mo deficiency because they are born before adequate stores for Mo can be acquired, they have rapid growth requiring increased intakes, and they frequently receive supplemental parenteral nutrition (SPN) and total parenteral nutrition (TPN) unsupplemented with molybdenum. Methods: To investigate Mo requirements of LBW infants (n = 16; birth weight, 1336 ± 351 g; gestational age, 29.8 ± 2.5 weeks; M ± SD), the authors collected all feeds, urine, and feces prior to TPN (baseline, n = 16, collections = 16), during TPN (n = 9, collections = 19), during SPN (n = 13, collections = 17), and after one week of full oral feeds (FOFs) of formula or human milk (FOF, n = 16, collections = 16). Results: Infant weights at collection times were: 1.3 ± 0.3 g, 1.27 ± 0.4 g, 1.4 ± 0.3 g, and 1.7 ± 0.5 g, respectively. Mo intake...