A Practically Unified Electrochemical Strategy for Ni-Catalyzed Decarboxylative Cross-Coupling of Aryl Trimethylammonium Salts
A Practically Unified Electrochemical Strategy for Ni-Catalyzed Decarboxylative Cross-Coupling of Aryl Trimethylammonium Salts
复制标题
DOI：
10.1021/acs.orglett.2c00408
复制
发表时间：
2022-03-25
期刊：
影响因子：
5.2
通讯作者：
Cao, Zhong-Yan
中科院分区：
文献类型：
--
作者：
Kong, Xianqiang;Chen, Yiyi;Cao, Zhong-Yan
通过将电催化和镍催化相结合，在温和条件下实现了4种α-氧代羧酸及其衍生物与芳基三甲基铵盐的脱羧交叉偶联反应。我们的策略提供了一个实用的方法来制备芳基酮，酰胺，酯，或醛。
By merging electrocatalysis and nickel catalysis, a unified strategy has been successfully applied to achieve the decarboxylative cross-coupling of four types of alpha-oxocarboxylic acids and their derivatives with aryl trimethylammonium salts under mild conditions. Our strategy provides a practical way for preparing aryl ketones, amides, esters, or aldehydes.