Maxillary ameloblastoma: Factors associated with risk of recurrence
Maxillary ameloblastoma: Factors associated with risk of recurrence
复制标题
上颌成釉细胞瘤：与复发风险相关的因素
DOI：
10.1002/hed.24720
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发表时间：
2017-05-01
影响因子：
2.9
通讯作者：
Ji, Tong
中科院分区：
文献类型：
--
作者：
Yang, Rong;Liu, Zheqi;Ji, Tong
背景上颌成釉细胞瘤很罕见，并且由于上颌骨和邻近结构的解剖结构而与侵袭性病程相关。本回顾性研究分析了复发的危险因素。方法对某三甲医院2005年至2015年报告的上颌骨成釉细胞瘤病例进行单因素和多因素Cox回归分析，找出与复发相关的临床病理和放射学因素。结果本研究共收治890例成釉细胞瘤患者，其中上颌骨成釉细胞瘤患者仅51例（5.7%）。成釉细胞瘤。中位随访时间为 56±28.65 个月。上颌成釉细胞瘤中，29 例（56.8%）为原发性，22 例（43.1%）为复发性。在单变量分析中，软组织或上颌窦侵犯以及原发性或复发性肿瘤状态是与复发显着相关的危险因素（分别为 p = .006 vs p = .025），而复发与手术方法之间的相关性则具有临界显着性（p = .08）。多变量Cox回归分析显示，软组织或上颌窦受累与复发显着相关(p = .023)。结论复发肿瘤以及软组织或上颌窦受累的肿瘤是上颌成釉细胞瘤患者复发的危险因素。 (c) 2017 年 Wiley periodicals, Inc. Head Neck 39: 996-1000, 2017
BackgroundMaxillary ameloblastomas are rare and associated with an aggressive course because of the anatomic composition of the maxilla and adjacent structures. The risk factors associated with recurrence were analyzed in this retrospective study.MethodsCases of maxillary ameloblastoma reported in a tertiary hospital from 2005 to 2015 were analyzed to identify clinicopathological and radiological factors associated with recurrence using univariate and multivariate Cox regression analyses.ResultsA total of 890 patients with ameloblastomas were treated in this study, of whom only 51 (5.7%) had maxillary ameloblastomas. The median follow-up period was 56 28.65 months. Of the maxillary ameloblastomas, 29 (56.8%) were primary and 22 (43.1%) were recurrent. Soft tissue or maxillary sinus invasion and primary or recurrent tumor status were risk factors significantly associated with recurrence in the univariate analyses (p = .006 vs p = .025, respectively), whereas the association between recurrence and surgical methods was borderline significant (p = .08). The multivariate Cox regression analysis showed that soft tissue or maxillary sinus involvement was significantly associated with recurrence (p = .023).ConclusionRecurrent tumors and tumors with soft tissue or maxillary sinus involvement were risk factors for recurrence among patients with maxillary ameloblastoma. (c) 2017 Wiley Periodicals, Inc. Head Neck 39: 996-1000, 2017