Specific Redistribution of Severe Acute Respiratory Syndrome Coronavirus 2 Variants in the Respiratory System and Intestinal Tract
Specific Redistribution of Severe Acute Respiratory Syndrome Coronavirus 2 Variants in the Respiratory System and Intestinal Tract
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DOI：
10.1093/cid/ciaa1617
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发表时间：
2021-11-01
影响因子：
11.8
通讯作者：
Zeng, Hui
中科院分区：
文献类型：
--
作者：
Du, Pengcheng;Song, Chuan;Zeng, Hui
对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）基因组序列的宿主内分析确定了2种病毒单倍型，由2019年冠状病毒病患者的呼吸道和肠道中的3种遗传连锁突变组成。时空数据表明，该患者最初有双重感染2 SARS-CoV-2变异，随后重新分布到2个系统。
Intrahost analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic sequences identified 2 viral haplotypes comprised of 3 genetically linked mutations from the respiratory and intestinal tracts of a patient with coronavirus disease 2019. Spatiotemporal data suggest that this patient initially had dual infection of 2 SARS-CoV-2 variants, which subsequently redistributed into the 2 systems.