Inhaled Nitric Oxide and Neuroprotection in Preterm Infants

Inhaled Nitric Oxide and Neuroprotection in Preterm Infants
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DOI:
10.1016/j.clp.2008.07.015
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发表时间:
2008-12-01
影响因子:
2.1
通讯作者:
Schreiber, Michael D.
Schreiber, Michael D.
中科院分区:
医学4区
文献类型:
--
作者:
Marks, Jeremy D.;Schreiber, Michael D.

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虽然吸入一氧化氮介导的慢性肺病和严重脑室内出血/脑室周围白质软化的减少无疑有助于改善神经发育结局,但吸入一氧化氮具有独立的神经保护作用。尽管这些数据令人鼓舞,但在推荐常规使用吸入一氧化氮对早产儿进行神经保护之前,还需要进一步的研究。
Although inhaled nitric oxide-mediated decreases in chronic lung disease and severe intraventricular hemorrhage/periventricular leukomalacia undoubtedly contribute to improved neurodevelopmental outcomes, inhaled nitric oxide has an independent neuroprotective effect. Although these data are encouraging, additional studies are required before recommending the routine use of inhaled nitric oxide for neuroprotection in preterm infants.