RESULTS OF A FILTERING PROCEDURE IN LOW TENSION GLAUCOMA
RESULTS OF A FILTERING PROCEDURE IN LOW TENSION GLAUCOMA
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DOI：
10.1007/bf02028653
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发表时间：
1989-01-01
影响因子：
1.6
通讯作者：
GEIJSSEN, HC
中科院分区：
文献类型：
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作者：
DEJONG, N;GREVE, EL;GEIJSSEN, HC
对20例低张力型青光眼患者的26只眼睛进行了“双瓣”Scheie滤过手术或小梁切除术，随访时间从1年到10年不等，中位数为3年。这26只眼睛包括两只作为对侧控制眼的第二眼，直到视野恶化。26只眼术前视野缺损进展，术后仅有2只眼视野缺损进一步进展。在16只未手术的对侧眼睛中，7只在相同的随访期间出现视野缺损的进展。在研究期间，这7只眼睛中的两只必须进行手术。手术眼与未手术眼的进展差异有统计学意义（P<0.01）。稀释手术使26只眼中的21只眼的IOP降低了20%或更多。术后1年，手术与未手术对侧眼平均眼压（IOP）差异有统计学意义，分别为6.8 mmHg（37%）。日变化从4.3 ~ 2.1 mmHg显著下降（P<0.001）。结论：低张力青光眼滤过手术不仅可以显著降低IOP，而且可以有效减缓视野的进一步恶化。
Twenty-six eyes of twenty patients with established low tension glaucoma, who had either a ‘double flap’ Scheie filtering operation or a trabeculectomy, were followed over a period ranging from one to ten years, with a median of three years. These 26 eyes include two second eyes that served as a contralateral control eye until the visual field deteriorated. All 26 eyes showed progression of visual field defects preoperatively, while postoperatively only 2 eyes showed further progression. Of the 16 nonoperated contralateral eyes, 7 showed progression of visual field defects over the same follow-up period. Two of these 7 eyes had to be operated during the study-period. The difference in progression between the operated and the non-operated eyes was significant (P<0.01). The diltering procedure provided a reduction in IOP of 20% or more in 21 of 26 eyes. There was a significant difference in the mean intraocular pressure (IOP) between the operated and the non-operated contralateral eye of 6.8 mmHg (37%) at one year postoperatively. The diurnal variation decreased highly significantly from 4.3 to 2.1 mmHg (P<0.001). It is concluded that filtering surgery in low tension glaucoma may result not only in a significant lowering of IOP, but is also effective in slowing further deterioration of the visual fields.