Severe acute respiratory syndrome (SARS): chest radiographic features in children
Severe acute respiratory syndrome (SARS): chest radiographic features in children
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DOI：
10.1007/s00247-003-1081-8
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发表时间：
2004-01-01
影响因子：
2.3
通讯作者：
Stringer, DA
中科院分区：
文献类型：
--
作者：
Babyn, PS;Chu, WCW;Stringer, DA
背景严重急性呼吸系统综合征（SARS）是一种最近被确认的病毒性疾病，与成人的高发病率和死亡率相关。关于其在儿童中的放射学表现的信息很少。Objective.本研究的目的是描述儿童SARS的影像学表现。材料和方法。我们提取了在多伦多、新加坡和香港的5家医院诊断的疑似（n=25）或可能（n=37）SARS患儿的影像学表现和病程的数据（n=62）。对可用的胸部X线片和胸部CT进行了审查，以确定是否存在以下影像学结果：气道疾病、支气管充气造影、气道炎症和支气管周围增厚、间质性疾病、胸腔积液和肺门淋巴结病。结果共有62例患者（疑似=25，可能=37）进行了SARS评估。患者年龄范围为5.5个月至17岁11.5个月（平均6岁10个月），男女比例为32：30。41名患者（66.1%）与其他可能、疑似或隔离病例密切接触; 10名患者（16.1%）最近在10天内去过世卫组织指定的疫区; 7名患者（11.2%）是从其他有SARS患者的医院转来的。三名病人没有与受影响地区有紧密接触或到医院接受治疗，亦没有到过受影响地区，根据他们的临床病征及居住在疫症流行地区的事实，他们被列为严重急性呼吸系统综合症个案。最主要的临床表现为发热（> 38 ℃）（100%）、咳嗽（62.9%）、流涕（22.6%）、肌痛（17.7%）、寒战（14.5%）和头痛（11.3%）。其他发现包括咽喉痛（9.7%）、胃肠道症状（9.7%）、寒战（8.1%）和嗜睡（6.5%）。一般来说，发烧和咳嗽是较年轻的儿童SARS病例（年龄
Background. Severe acute respiratory syndrome (SARS) is a recently recognized condition of viral origin associated with substantial morbidity and mortality rates in adults. Little information is available on its radiologic manifestations in children. Objective. The goal of this study was to characterize the radiographic presentation of children with SARS. Materials and methods. We abstracted data (n=62) on the radiologic appearance and course of SARS in pediatric patients with suspect (n=25) or probable (n=37) SARS, diagnosed in five hospital sites located in three cities: Toronto, Singapore, and Hong Kong. Available chest radiographs and thoracic CTs were reviewed for the presence of the following radiographic findings: airspace disease, air bronchograms, airways inflammation and peribronchial thickening, interstitial disease, pleural effusion, and hilar adenopathy. Results. A total of 62 patients (suspect=25, probable=37) were evaluated for SARS. Patient ages ranged from 5.5 months to 17 years and 11.5 months (average, 6 years and 10 months) with a female-to-male ratio of 32:30. Forty-one patients (66.1%) were in close contact with other probable, suspect, or quarantined cases; 10 patients (16.1%) had recently traveled to WHO-designated affected areas within 10 days; and 7 patients (11.2%) were transferred from other hospitals that had SARS patients. Three patients, who did not have close/hospital contact or travel history to affected areas, were classified as SARS cases based on their clinical signs and symptoms and on the fact that they were living in an endemic area. The most prominent clinical presentations were fever, with a temperature over 38 degreesC (100%), cough (62.9%), rhinorrhea (22.6%), myalgia (17.7%), chills (14.5%), and headache (11.3%). Other findings included sore throat (9.7%), gastrointestinal symptoms (9.7%), rigor (8.1%), and lethargy (6.5%). In general, fever and cough were the most common clinical presentations amongst younger pediatric SARS cases (age