Outbreaks of gastroenteritis caused by SRSVs from 1987 to 1992 in Kyushu, Japan: Four outbreaks associated with oyster consumption
Outbreaks of gastroenteritis caused by SRSVs from 1987 to 1992 in Kyushu, Japan: Four outbreaks associated with oyster consumption
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1987年至1992年日本九州爆发由SRSV引起的胃肠炎：四次爆发与牡蛎消费有关
DOI：
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发表时间：
1999
影响因子：
13.6
通讯作者：
R. Otsu
中科院分区：
文献类型：
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作者：
R. Otsu
从1987年到1992年，九州地区发生了18起急性非细菌性胃肠炎暴发。最常见的症状是腹泻、呕吐、恶心和腹部绞痛。在52份标本中检出小圆结构病毒（SRSVs）17起暴发疫情的116份粪便标本中，电镜法检测阳性率为44.8%，42例患者的抗体水平显着增加免疫电镜（IEM）法检测12起暴发疫情的52对血清标本，阳性率为80.7%;对8起暴发疫情的35份样品进行免疫印迹（WB）检测，阳性率为51.4%。然而，根据WB方法，在8次爆发中的3次中未观察到与参考抗原条（SRSV-9/Tokyo 86-510，63 kDa）的抗原-抗体反应。检测到的病毒被认为是这些暴发的病原体。在5起与食用生蚝有关的暴发疫情中，有4起的SRSV感染与食用生蚝密切相关。
From 1987 to 1992, 18 outbreaks of acute non-bacterial gastroenteritis occurred in Kyushu district. The most common symptoms were diarrhea, vomiting, nausea and abdominal cramp. Small round structured viruses (SRSVs) were detected in 52 (44.8%) of 116 stool samples from 17 outbreaks by the electron microscopy (EM) method, and a significant increase in the antibody level was noted in 42 (80.7%) of 52 paired serum samples from 12 outbreaks by the immune electron microscopy (IEM) method and in 18 (51.4%) of 35 samples from 8 outbreaks by the western blot (WB) method. However, according to the WB method, antigen-antibody reaction was not observed to reference antigen strips (SRSV-9/Tokyo 86-510, 63kDa) in three of the 8 outbreaks. The detected virus was regarded as an etiologic agent for these outbreaks. In four of 5 outbreaks which appeared associated with eating raw oysters, there was a close relation between SRSV infection and consumption of raw oysters.