Fish consumption, mercury exposure and serum antinuclear antibody in Amazonians
Fish consumption, mercury exposure and serum antinuclear antibody in Amazonians
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DOI：
10.1080/09603120600734147
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发表时间：
2006-08-01
影响因子：
3.2
通讯作者：
Cordeiro, George W. O.
中科院分区：
文献类型：
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作者：
Alves, Maria Francinaire A.;Fraiji, Nelson A.;Cordeiro, George W. O.
在疟疾发病率高的亚马逊人口中，研究了鱼类对固有汞的接触情况。高食鱼河流相比，城市（玛瑙斯居民）低食鱼河流方面的汞暴露（头发汞）和血清抗核抗体（ANA）。大多数河鱼（99.0%）每天吃鱼，而对照组只有3%。高甲基汞鱼类的消费频率（45.5%）比对照组（18.8%）的河流。河鱼的平均发汞（34.5 ppm）显著高于对照组（1.0 ppm）。尽管河鱼人群ANA阳性率（12.4%）高于对照人群（2.9%），但发汞与ANA无显著相关性。河流流域疟疾报告的高流行率与汞暴露和血清ANA均无关。食用鱼类接触MMHg不太可能导致自身免疫功能障碍。
Exposure to intrinsic Hg in fish was studied in Amazon populations with high prevalence of malaria disease. High fish-eater riverines were compared to urban (Manaus residents) low fish-eater riverines in regards to Hg exposure (hair-Hg) and serum antinuclear antibodies (ANA). Most riverines (99.0%) ate fish daily compared to only 3% of controls. Fish species high in MeHg was consumed more frequently (45.5%) by riverines than controls (18.8%). Mean hair-Hg (34.5 ppm) of riverines was significantly higher than controls (1.0 ppm). Although positive serum ANA was more frequently observed in riverine fish-eaters (12.4%) than controls (2.9%), there was no significant association between hair-Hg and ANA. High prevalence of malaria reporting among riverines was neither associated with Hg exposure nor with serum ANA. An autoimmune dysfunction is unlikely to occur as a result of MMHg exposure due to fish consumption.