Emerging Opportunities in the Biomedical Applications of Dendrimers
Emerging Opportunities in the Biomedical Applications of Dendrimers
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DOI：
10.1007/s10904-017-0768-5
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发表时间：
2018-03-01
影响因子：
4
通讯作者：
Agatemor, Christian
中科院分区：
文献类型：
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作者：
Abd-El-Aziz, Alaa S.;Agatemor, Christian
医疗领域仍然面临着许多未满足的需求的挑战，这促使人们对解决方案进行严格的研究。树枝状聚合物正在成为许多未满足的临床需求的创新解决方案。事实上，商业化的树枝状聚合物基因转染技术已经存在，并且正在努力将许多其他树枝状聚合物产品转化为市场以帮助患者。在这里，我们回顾了树枝状大分子药物输送技术、诊断平台和抗菌药物方面正在进行的工作。我们的目标是激发对树突支架的不断探索，以解决生物医学领域的许多问题。
The medical field remains challenged with many unmet needs, prompting rigorous research for solutions. Dendrimers are emerging as innovative solutions to many unmet clinical needs. Indeed, commercial dendrimer-enabled gene transfection technologies exist and work is ongoing to translate many other dendrimer products into the market to assist patients. Here, we review the ongoing work on dendrimer-enabled drug delivery technologies, diagnostic platforms, and antimicrobial agents. Our goal is to inspire the continuous exploration of the dendritic scaffold to address many issues in the biomedical landscape.