Psychogenic non-epileptic seizures and functional motor symptoms: A common phenomenology?

Psychogenic non-epileptic seizures and functional motor symptoms: A common phenomenology?
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DOI:
10.1016/j.jns.2016.06.045
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发表时间:
2016-09-15
影响因子:
4.4
通讯作者:
Gambini, Orsola
Gambini, Orsola
中科院分区:
医学3区
文献类型:
--
作者:
Demartini, Benedetta;Goeta, Diana;Gambini, Orsola

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目的:最近的研究试图从人口统计学、临床和心理学的角度比较受心因性非癫痫性发作(PNES)影响的患者与受功能性运动症状(FMS)影响的患者。然而,结果是相当有争议的,并没有得出重要的结论。我们的研究的目的是评估的心理学的两组评估水平的分离及其子组件,述情障碍和内感受性敏感性的PNES患者和FMS.Methods:我们进行了一项横断面研究,招募20例PNES患者,20例FMS和20名健康受试者作为对照组。所有受试者均接受:分离体验量表(DES)、躯体形式分离问卷(SDQ-20)、剑桥人格解体量表(CDS)、多伦多述情障碍量表(TAS-20)、汉密尔顿抑郁量表(HAM-D)、汉密尔顿焦虑量表(HAM-A)、心跳检测任务。此外,在DES,心理形式分离的措施,PNES患者得分显着高于健康受试者。另一方面,受FMS影响的患者在SDQ上的评分显著高于健康对照组,但他们没有报告更多的CDS分离经历。PNES和FMS患者的述情障碍显著高于健康对照组,其中三分之一患者TAS-20评分>61分。意义:我们的数据显示PNES和FMS患者存在不同的心理机制。这也可能对治疗产生潜在影响。(C)2016爱思唯尔B. V.保留所有权利。
Objective: Recent studies have attempted to compare patients affected by psychogenic non-epileptic seizures (PNES) to patients affected by functional motor symptoms (FMS) from a demographic, clinical and psychological perspective. Nevertheless, results are quite controversial and significant conclusions have not been drawn. The aim of our study was to evaluate the phenomenology of psychology of the two groups assessing levels of dissociation and its subcomponents, alexithymia and interoceptive sensitivity in patients with PNES and in patients with FMS.Methods: We conducted a cross-sectional study recruiting 20 patients with PNES, 20 patients with FMS and 20 healthy subjects as a control group. All subjects underwent: Dissociative Experience Scale (DES), Somatoform Dissociation Questionnaire (SDQ-20), Cambridge Depersonalization Scale (CDS), Toronto Alexithymia Scale (TAS-20), Hamilton Rating Scale for Depression (HAM-D), Hamilton Rating Scale for anxiety (HAM-A), heart beat detection task.Results: Our data suggest that PNES group scored significantly higher than the healthy control group on a measure of detachment (CDS). Also at the DES, a measure of psychoform dissociation, PNES patients scored significantly higher than healthy subjects. On the other hand patients affected by FMS scored significantly higher than the healthy control group on the SDQ but they did not report more experiences of detachment on the CDS. Patients affected by PNES and FMS were significantly more alexithymic than healthy controls, with a third of them scoring >61 on the TAS-20.Significance: Our data show different psychological mechanisms underlying patients with PNES and patients with FMS. This might lead also to potential implications for treatment. (C) 2016 Elsevier B.V. All rights reserved.