Characteristic of EBT-XD and EBT3 radiochromic film dosimetry for photon and proton beams
Characteristic of EBT-XD and EBT3 radiochromic film dosimetry for photon and proton beams
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DOI：
10.1088/1361-6560/aab1ee
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发表时间：
2018-03-01
影响因子：
3.5
通讯作者：
Kuess, Peter
中科院分区：
文献类型：
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作者：
Khachonkham, Suphalak;Dreindl, Ralf;Kuess, Peter
最近，一种新型的辐射变色胶片，EBT-XD胶片，已被引入用于高剂量放射治疗。EBT-XD薄膜包含与EBT 3薄膜相同的结构，但具有略微不同的成分和更薄的活性层。这项研究基准EBT-XD对EBT 3膜为6 MV和10 MV的光子束，以及97.4 MeV和148.2 MeV的质子束和15-100 kV的X射线。研究了剂量学和胶片阅读特性，如照射后暗化、胶片取向效应、横向响应伪影（LRA）、胶片灵敏度、能量和光束质量依赖性。此外，在布拉格峰的淬火效果进行了研究，为一个单一的质子束能量的两种薄膜类型，此外，测量进行了扩展的布拉格峰。EBT-XD薄膜表现出与EBT 3相同的薄膜暗化特性。与剂量为2000 cGy的EBT 3相比，EBT-XD的纵向和横向方向之间的影响降低了3.1%（像素值）。对于所有研究的剂量范围，EBT-XD膜的LRA降低。对于高于500 cGy的剂量，EBT-XD胶片的灵敏度上级优于EBT 3。此外，EBT-XD显示出类似的光子和质子辐照的剂量响应，具有低能量和光束质量依赖性。两种类型的薄膜的淬火效果均为10%。活性层厚度的略微减小和EBT-XD的不同成分配置导致了膜取向效应和LRA的降低，以及光子和质子束在高剂量区的灵敏度增加。总的来说，EBT-XD胶片在胶片阅读特性方面有所改善，并在光子和质子束的高剂量区域中显示出优势。
Recently, a new type of radiochromic film, the EBT-XD film, has been introduced for high dose radiotherapy. The EBT-XD film contains the same structure as the EBT3 film but has a slightly different composition and a thinner active layer. This study benchmarks the EBT-XD against EBT3 film for 6 MV and 10 MV photon beams, as well as for 97.4 MeV and 148.2 MeV proton beams and 15-100 kV x-rays. Dosimetric and film reading characteristics, such as post irradiation darkening, film orientation effect, lateral response artifact (LRA), film sensitivity, energy and beam quality dependency were investigated. Furthermore, quenching effects in the Bragg peak were investigated for a single proton beam energy for both film types, in addition measurements were performed in a spread-out Bragg peak. EBT-XD films showed the same characteristic on film darkening as EBT3. The effects between portrait and landscape orientation were reduced by 3.1% (in pixel value) for EBT-XD compared to EBT3 at a dose of 2000 cGy. The LRA is reduced for EBT-XD films for all investigated dose ranges. The sensitivity of EBT-XD films is superior to EBT3 for doses higher than 500 cGy. In addition, EBT-XD showed a similar dosimetric response for photon and proton irradiation with low energy and beam quality dependency. A quenching effect of 10% was found for both film types. The slight decrease in the thickness of the active layer and different composition configuration of EBT-XD resulted in a reduced film orientation effect and LRA, as well as a sensitivity increase in high-dose regions for both photon and proton beams. Overall, the EBT-XD film improved regarding film reading characteristics and showed advantages in the high-dose region for photon and proton beams.