Examination of micro-superficial lesions of up to 5 mm in size in the pharyngolaryngeal region
Examination of micro-superficial lesions of up to 5 mm in size in the pharyngolaryngeal region
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DOI：
10.1017/s0022215122001761
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发表时间：
2022-08-02
影响因子：
1.7
通讯作者：
Takeno，S.
中科院分区：
文献类型：
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作者：
Ueda，T.;Yumii，K.;Takeno，S.
目的对于低级别上皮内瘤变病例，大小等于或小于5mm的咽部病变通常不会发展为浸润性癌。然而，最近也出现了小于5mm且生长迅速的微浅表病变。本研究旨在确定大小等于或小于5mm的病变优先进展的特征。方法回顾性分析55例直径小于或等于5mm的病变的大体表现、内镜表现和病理结果，以确定区分鳞状细胞癌或高级别上皮内瘤变与低级别上皮内瘤变或非异型病变的因素。结果该方法的总体灵敏度、特异度、准确度、背景染色和乳头内毛细血管袢型对鳞状细胞癌或高级别上皮内瘤变与低级别上皮内瘤变或非异型病变的阳性和阴性预测价值均为100%。结论基于窄带成像的背景染色和乳头内毛细血管袢型有助于对小于等于5mm的病变进行病理检查。
ObjectiveFor low-grade intraepithelial neoplasia cases, pharyngolaryngeal lesions equal to or less than 5 mm in size do not generally progress to invasive carcinoma. However, micro-superficial lesions equal to or less than 5 mm that showed rapid growth have been recently encountered. This study aimed to identify the characteristics of preferential progression of lesions equal to or less than 5 mm in size.MethodGross findings, endoscopic findings and pathological results of 55 lesions measuring equal to or less than 5 mm in diameter were retrospectively reviewed to identify factors that distinguish squamous cell carcinoma or high-grade intraepithelial neoplasia from low-grade intraepithelial neoplasia or non-atypia lesions.ResultsThe overall sensitivity, specificity, accuracy, and positive and negative predictive value of background colouration and intrapapillary capillary loop pattern in differentiation of squamous cell carcinoma or high-grade intraepithelial neoplasia from low-grade intraepithelial neoplasia or non-atypia lesions were all 100 per cent.ConclusionDiagnosis based on background colouration and the intrapapillary capillary loop pattern on narrow-band imaging facilitates the pathological examination of lesions measuring equal to or less than 5 mm.