Quality of life and patients' satisfaction in chronic urticaria and respiratory allergy

Quality of life and patients' satisfaction in chronic urticaria and respiratory allergy
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DOI:
10.1034/j.1398-9995.2003.00091.x
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发表时间:
2003-07-01
期刊:
影响因子:
12.4
通讯作者:
Canonica, GW
Canonica, GW
中科院分区:
医学1区
文献类型:
--
作者:
Baiardini, I;Giardini, A;Canonica, GW

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背景:关于慢性荨麻疹(CU)对患者生活质量(QoL)影响的文章很少。本研究的目的是评估CU患者的生活质量,重点关注健康状况和主观满意度。我们采用了两种通用工具:SF-36(健康状况问卷)和SAT-P(满意度)。方法:21例未接受治疗的CU患者(5例男性,16例女性;年龄46.3 ± 12.4岁)入组。将CU患者的SF-36和SAT-P评分与27例呼吸道过敏患者的评分进行比较。分别将608名和241名意大利健康受试者的已发表参考值用作SF-36和SAT-P的对照。与过敏性患者相比,CU患者的身体功能评分显著降低(P = 0.046),生理角色(P = 0.01),身体疼痛(P = 0.0001),一般健康状况(P = 0.0043)和角色情感(P = 0.04),与参考样本相比,SF-36各领域得分均较低(P < 0.0001)。与呼吸道过敏患者和参考样本相比,CU患者的SAT-P评分显着降低,在许多方面的日常living.Conclusions:这些结果显示了显着的影响,CU患者的健康状况和主观满意度:症状影响日常生活,限制和损害身体和情感功能,并作为一个间接负担的生活满意度。
Background: Few articles are available about chronic urticaria (CU) impact on patients' quality of life (QoL). The aim of our study was to evaluate QoL in CU patients both focusing on health status and subjective satisfaction. We adopted two generic tools: SF-36 (an health status questionnaire) and SAT-P (a satisfaction profile).Methods: Twenty-one untreated patients (five males, 16 females; aged 46.3 +/- 12.4) affected by CU, were enrolled. SF-36 and SAT-P scores of CU patients were compared with scores of a group of 27 patients with respiratory allergy. Published reference values of 608 and 241 Italian healthy subjects were used as controls, respectively, for SF-36 and SAT-P.Results: Patients with CU compared with allergic patients referred significantly lower scores in physical functioning (P = 0.046), role physical (P = 0.01), bodily pain (P = 0.0001), general health (P = 0.0043) and role emotional (P = 0.04), and compared with reference sample reported lower scores in all SF-36 domains (P < 0.0001). SAT-P scores of CU patients compared with patients with respiratory allergy and with reference sample were significantly lower in many aspects of daily life.Conclusions: These results show a significant impact on health status and on subjective satisfaction in patients with CU: the symptoms affect everyday life, limiting and impairing physical and emotional functioning, and acts as an indirect burden on life satisfaction.