In vivo anterior cruciate ligament elongation in response to axial tibial loads.

In vivo anterior cruciate ligament elongation in response to axial tibial loads.
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体内前交叉韧带伸长响应轴向胫骨负荷。

DOI:
10.1007/s00776-009-1325-z
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发表时间:
2009-05
影响因子:
1.7
通讯作者:
Li, Guoan
Li, Guoan
中科院分区:
医学4区
文献类型:
--
作者:
Hosseini, Ali;Gill, Thomas J.;Li, Guoan

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前交叉韧带(ACL)在体内变形的知识是了解ACL损伤机制和改善手术重建的损伤ACL的基础。本研究采用双透视和磁共振成像(MRI)技术,研究了膝关节在不同屈曲角度下空载(<10 N)和满载(轴向胫骨载荷)时ACL的相对伸长。对9名健康受试者进行MRI扫描,并使用双透视系统(0°-45°屈曲角)在一侧膝关节无负荷后进行全体重成像。ACL采用三种模型进行分析:单一中央束;前内侧和后外侧(双功能)束;以及多个(8个)表面纤维束。前内侧束在30°时相对伸长最大,为4.4% ± 3.4%;后外侧束在15°时相对伸长最大,为5.9% ± 3.4%。ACL后部的ACL表面纤维束长度短于前部。然而,通过将胫骨轴向载荷从无载荷增加到全身重量,在屈曲30°时,一个后外侧纤维束的峰值相对伸长达到13%以上,而一个前内侧纤维束的峰值相对伸长仅为3%左右。数据定量地表明,在外部载荷下,ACL经历不均匀的伸长,后部纤维束比前部纤维束拉伸更多。
The knowledge of in vivo anterior cruciate ligament (ACL) deformation is fundamental for understanding ACL injury mechanisms and for improving surgical reconstruction of the injured ACL. This study investigated the relative elongation of the ACL when the knee is subject to no load (<10 N) and then to full body weight (axial tibial load) at various flexion angles using a combined dual fluoroscopic and magnetic resonance imaging (MRI) technique. Nine healthy subjects were scanned with MRI and imaged when one knee was subject to no load and then to full body weight using a dual fluoroscopic system (0°–45° flexion angles). The ACL was analyzed using three models: a single central bundle; an anteromedial and posterolateral (double functional) bundle; and multiple (eight) surface fiber bundles. The anteromedial bundle had a peak relative elongation of 4.4% ± 3.4% at 30° and that of the posterolateral bundle was 5.9% ± 3.4% at 15°. The ACL surface fiber bundles at the posterior portion of the ACL were shorter in length than those at the anterior portion. However, the peak relative elongation of one posterolateral fiber bundle reached more than 13% whereas one anteromedial fiber bundle reached a peak relative elongation of only about 3% at 30° of flexion by increasing the axial tibial load from no load to full body weight. The data quantitatively demonstrated that under external loading the ACL experiences nonhomogeneous elongation, with the posterior fiber bundles stretching more than the anterior fiber bundles.
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