Branched connections to the septum and to the entorhinal cortex from the hippocampus, amygdala, and diencephalon in the rat
Branched connections to the septum and to the entorhinal cortex from the hippocampus, amygdala, and diencephalon in the rat
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DOI：
10.1016/0361-9230(96)00033-0
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发表时间：
1996-01-01
影响因子：
3.8
通讯作者：
Bentivoglio, M
中科院分区：
文献类型：
--
作者：
Calderazzo, L;Cavalheiro, EA;Bentivoglio, M
用荧光示踪剂Fast Blue和Diamidino Huang对大鼠大脑中隔和内嗅皮质发出分支投射的神经细胞群进行了研究。在CA1区和下丘脑底核的时间水平上一致地观察到双标记锥体神经元，它们至少占内嗅觉注射逆行标记细胞的50%；杏仁核中也有双标记神经元，它们主要分布在基底复合体中；在下丘脑的一些核团中可见散在的双标记神经元，在视前区略占优势。最后，在丘脑中线，尤其是丘脑室旁核，可见少量双标细胞。在这些结构中，双标细胞位于注射部位的两侧。目前的数据表明，隔和内嗅皮层通过轴突分支紧密相连，这些轴突来自各种端脑和间脑来源。
Neuronal cell populations giving origin to bifurcating projections to the septum and the entorhinal cortex were studied in the rat by means of double retrograde labeling using the fluorescent tracers Fast Blue and Diamidino Yellow, Double labeled pyramidal neurons were consistently detected in the temporal level of the CA1 area and subiculum of the hippocampal formation, where they represented at least 50% of the cells retrogradely labeled from the entorhinal injections, Double labeled neurons were also detected in the amygdala, where they prevailed in the basal complex, Scattered double labeled neurons were observed in a number of hypothalamic nuclei, with a slight predominance in the preoptic region. Finally, a few double labeled cells were detected in the midline thalamus, and especially in the thalamic paraventricular nucleus, In all these structures, double labeled neurons were located ispilaterally to the injection sites. The present data indicate that the septum and entorhinal cortex are tightly interconnected by axonal bifurcations deriving from a variety of telencephalic and diencephalic sources.