The ACVD task force on canine atopic dermatitis (XIV): clinical manifestations of canine atopic dermatitis
The ACVD task force on canine atopic dermatitis (XIV): clinical manifestations of canine atopic dermatitis
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DOI：
10.1016/s0165-2427(01)00346-4
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发表时间：
2001-09-20
影响因子：
1.8
通讯作者：
DeBoer, DJ
中科院分区：
文献类型：
--
作者：
Griffin, CE;DeBoer, DJ
犬特应性疾病，包括那些皮肤病变，已被描述多年。不幸的是，早期的描述往往未能建立明确的指导方针，考虑患者的特应性，和诊断特应性皮炎（AD）的标准有不同的作者。20世纪60年代至80年代发表的较大病例系列表明，AD最常见的临床表现是瘙痒，特别是面部、耳朵、爪子、四肢和/或腹部瘙痒。在早期报告中，并不总是清楚是否始终对患者仔细进行了消除其他鉴别诊断的检测;因此，一些描述可能包括患有AD以外疾病或除AD外疾病的患者。关于病例系列中AD临床表现的共识点包括：瘙痒症从年轻时开始出现，可能是季节性的;以及面部、四肢、腋窝或腹部的明显病变累及。存在关于品种和性别倾向的信息，可能代表区域或时间变异性。关于AD犬中观察到的病变描述，临床报告各不相同。这反映了可能与继发性并发症病变的混淆，并强调了犬AD原发性病变的存在和性质尚不真正清楚的事实。(C)2001爱思唯尔科技有限公司。保留所有权利。
Canine atopic diseases, including those with skin lesions, have been described for many years. Unfortunately, early descriptions often failed to establish definitive guidelines for considering a patient atopic, and criteria for diagnosing atopic dermatitis (AD) have varied from author to author. Larger case-series published from the 1960s to the 1980s suggested that the most common clinical manifestation of AD was pruritus, particularly of the face, ears, paws, extremities, and/or ventrum. It is not always clear that testing to eliminate other differential diagnoses was always carefully performed on patients in early reports; therefore, some descriptions could include patients affected with diseases other than or in addition to AD. Points of consensus regarding clinical manifestations of AD in case-series include the presence of pruritus beginning at a young age, possibly seasonally; and a prominent lesional involvement of the face, extremities, axillae or ventrum. Conflicting information on breed and sex predispositions is present, perhaps representing regional or temporal variability. Clinical reports vary, in regard to the description of lesions seen in dogs with AD. This reflects a possible confusion with lesions of secondary complications, and highlights the fact that the existence and nature of primary lesions of canine AD are not truly known. (C) 2001 Elsevier Science B.V. All rights reserved.