Improved stability and controlled release of CLA with spray-dried microcapsules of OSA-modified starch and xanthan gum
Improved stability and controlled release of CLA with spray-dried microcapsules of OSA-modified starch and xanthan gum
复制标题
使用 OSA 改性淀粉和黄原胶喷雾干燥微胶囊提高 CLA 的稳定性和控制释放
DOI：
10.1016/j.carbpol.2016.03.078
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发表时间：
2016-08-20
影响因子：
11.2
通讯作者：
Li, Zhaofeng
中科院分区：
文献类型：
--
作者：
He, Huizi;Hong, Yan;Li, Zhaofeng
本研究的目的是提高CLA的稳定性，并允许其控制释放，通过将其与辛烯基琥珀酸酐（OSA）淀粉和黄原胶（XG）以三种比例（OSA/XG：60/1、80/1和100/1，w/w）的组合包封。使用FTIR和TGA检查壁材料。采用激光粒度分析仪（LPS）和扫描电镜（SEM）对微胶囊进行了表征。通过顶空法监测微胶囊的氧化。结果显示，以60/1的OSA/XG比率产生的微胶囊对CLA提供了上级抗氧化保护。当CLA-微胶囊经受模拟人胃肠道系统的条件时，12.1%-50.1%的CLA被释放。CLA封装在喷雾干燥的OSA/XG微胶囊似乎是一种有效的技术，提供了良好的抗氧化保护，并可能是有用的功能性脂质或其他生物活性成分的小肠靶向输送。(C)2016爱思唯尔有限公司版权所有。
The objective of this investigation was to improve the stability of CLA and to allow for its controlled release by encapsulating it with combinations of octenyl-succinic anhydride (OSA) starch and xanthan gum (XG) in three ratios (OSA/XG: 60/1, 80/1, and 100/1, w/w). The wall material was examined using FTIR and TGA. The microcapsules were characterized by laser particle size analysis (LPS) and SEM. Oxidation of the microcapsules was monitored by headspace method. The results revealed that microcapsules created with an OSA/XG ratio of 60/1 provided superior protection to CLA against oxidation. When CLA-microcapsules were subjected to conditions simulating those in the human gastrointestinal system, 12.1%-50.1% of the CLA was released. CLA encapsulation in spray-dried microcapsules of OSA/XG appears to be an effective technique that provides good protection against oxidation and could be useful in the targeted delivery of functional lipids or other bioactive components to the small intestine. (C) 2016 Elsevier Ltd. All rights reserved.