Feasibility of inducing new intermuscular coordination patterns through an electromyographic signal-guided training in the upper extremity: a pilot study
Feasibility of inducing new intermuscular coordination patterns through an electromyographic signal-guided training in the upper extremity: a pilot study
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通过上肢肌电信号引导训练诱导新的肌间协调模式的可行性：一项试点研究
DOI：
10.1109/embc46164.2021.9630089
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Jinsook Roh
中科院分区：
文献类型：
--
作者：
Gang Seo;Jeong;Hyung‐Soon Park;Jinsook Roh
肌间协调异常一直是脑卒中后上肢康复领域的研究热点。相对较新的研究已经量化了改变的“肌肉协同作用”，一组肌肉的独特的共同激活模式，其特征在于中风引起的异常肌间协调。尽管如此，靶向改变的肌肉协同作用是否会改善中风引起的运动障碍并改善运动功能仍然是未知的。我们的最终目标是设计一个运动方案，修改异常的肌肉协同作用，改善运动功能，在UE中风后。在这项研究中，一个肌电图（EMG）信号引导的运动协议，其目标是改变肘屈肌协同作用的可行性，在健康受试者进行了测试。四名神经系统完整的成年人参加了为期六周的等长运动，以激活两个主要的肘屈肌，二头肌和肱桡肌，在隔离。参与者在虚拟三维（3D）力空间中进行等长伸展，以评估在训练的第0周，第2周，第4周和第6周评估期间肌肉协同作用的任何潜在变化。同时采集12块UE肌肉的肌电图和三维力。一个非负矩阵分解（NMF）被应用于环境管理小组，以确定协同增效作用。从训练的第三到第四周，当参与者打算使用新学到的运动技能时，他们能够单独激活目标肌肉对，并诱导新出现的协同肌肉群的形成。当参与者练习扩展他们的肌间协调模式时，他们对训练UE的运动控制得到了改善。这些研究结果表明，我们的等长运动方案可以潜在地调节受损的肌肉协调性，从而有利于中风幸存者在日常生活活动（ADL）中的表现，并最终提高他们的生活质量。
Abnormal intermuscular coordination has been highlighted in the field of post-stroke upper extremity (UE) rehabilitation. Relatively recent studies have quantified the altered "muscle synergies", distinctive co-activation patterns of a group of muscles, which characterize the stroke-induced abnormal intermuscular coordination. Nonetheless, whether targeting the altered muscle synergy(ies) would ameliorate the stroke-induced motor impairment and improve motor function remains unknown. Our ultimate aim is to design an exercise protocol that modifies abnormal muscle synergies and improves motor function in UE after stroke. In this study, the feasibility of an electromyographic (EMG) signal-guided exercise protocol, which targeted the alteration of an elbow flexor synergy, was tested in healthy subjects. Four neurologically intact adults participated in a six-week isometric exercise to activate two major elbow flexor muscles, biceps and brachioradialis, in isolation. Participants performed an isometric reaching in a virtual three-dimensional (3D) force space to assess any potential changes in muscle synergies during the assessment at week zero, two, four, and six of the training. EMGs of 12 UE muscles and 3D forces were collected simultaneously. A non-negative matrix factorization (NMF) was applied to the EMGs to identify synergies. From the third-to-fourth week of the training, when the participants intended to use the newly learned motor skill, they were able to activate the targeted muscle pair in isolation and induce the formation of newly emerging synergistic muscle groups. As the participants practiced to expand their repertoire of intermuscular coordination patterns, their motor control of the trained UE was improved. These findings suggest that our isometric exercise protocol can potentially modulate impaired muscle coordination in a way that benefits stroke survivor’s performance in activities of daily living (ADLs) and, eventually, their quality of life.
影响因子：
14.5
作者：
DEWALD, JPA;POPE, PS;RYMER, WZ
通讯作者：
RYMER, WZ
影响因子：
2.5
作者：
Laine, Christopher M.;Valero-Cuevas, Francisco J.
通讯作者：
Valero-Cuevas, Francisco J.
影响因子：
2.5
作者：
Roh, Jinsook;Rymer, William Z.;Beer, Randall F.
通讯作者：
Beer, Randall F.