Traffic noise and risk of myocardial infarction
Traffic noise and risk of myocardial infarction
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DOI：
10.1097/01.ede.0000147104.84424.24
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发表时间：
2005-01-01
期刊：
影响因子：
5.4
通讯作者：
Ising, H
中科院分区：
文献类型：
--
作者：
Babisch, WF;Beule, B;Ising, H
背景：噪声应激相关的心血管反应在生物学上是可信的。关于交通噪声与缺血性心脏病关系的流行病学研究表明，暴露在高水平交通噪声中的人发生心肌梗死的风险更高。方法：为了确定道路交通噪声对心肌梗死(MI)发病率的风险，我们在柏林进行了一项以医院为基础的病例对照研究。我们招募了从1998年到2001年确诊为心肌梗塞的连续患者(n=1881)，年龄20-69岁。对照组(n=2234)按性别、年龄和医院配对。根据城市噪声地图，确定每个研究对象的室外交通噪声水平。结果：白天暴露在70分贝(A)以上的男性与噪声水平不超过60分贝(A)的男性相比，调整后的优势比为1.3(95%可信区间=0.88-1.8)。在目前住址居住至少10年的男性样本中，赔率比为1.8(1.0-3.2)。结论：研究结果支持了长期暴露在高水平交通噪声中会增加心血管疾病风险的假设。
Background: The biologic plausibility for noise stress-related cardiovascular responses is well established. Epidemiologic studies on the relationship between transportation noise and ischemic heart disease suggest a higher risk of myocardial infarction in subjects exposed to high levels of traffic noise.Methods: To determine the risk of road traffic noise for the incidence of myocardial infarction (MI), we carried out a hospital-based case-control study in the city of Berlin. We enrolled consecutive patients (n = 1881), age 20-69 years, with confirmed diagnosis of MI from 1998 through 2001. Controls (n = 2234) were matched according to sex, age, and hospital. Outdoor traffic noise level was determined for each study subject based on noise maps of the city. Standardized interviews were conducted to assess possible confounding factors and the annoyance from various noise sources.Results: The adjusted odds ratio for men exposed to sound levels of more than 70 dB(A) during the day was 1.3 (95% confidence interval = 0.88-1.8) compared with those where the sound level did not exceed 60 dB(A). In the subsample of men who lived for at least 10 years at their present address, the odds ratio was 1.8 (1.0-3.2). Noise-exposed women were not at higher risk.Conclusions: The results support the hypothesis that chronic exposure to high levels of traffic noise increases the risk for cardiovascular diseases.