Combined large-cell neuroendocrine carcinoma and endometrioid adenocarcinoma of the endometrium: A case report and survey of related literature
Combined large-cell neuroendocrine carcinoma and endometrioid adenocarcinoma of the endometrium: A case report and survey of related literature
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DOI：
10.1111/jog.12881
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发表时间：
2016-02-01
影响因子：
1.6
通讯作者：
Nishida, Haruto
中科院分区：
文献类型：
--
作者：
Matsumoto, Harunobu;Nasu, Kaei;Nishida, Haruto
子宫内膜原发性大细胞神经内分泌癌极为罕见，且预后不良。本报告描述了一个合并大细胞神经内分泌癌和子宫内膜类腺癌的病例，诊断为IIIA期。患者接受了手术和化疗，20个月来一直很好，没有疾病的迹象。这种罕见肿瘤的最佳治疗方法尚未确定。由于其罕见性和变异性，很难建立一个循证治疗方案。
Primary large-cell neuroendocrine carcinoma of the endometrium is extremely rare and has a poor prognosis. This report describes a case of combined large-cell neuroendocrine carcinoma and endometrioid adenocarcinoma of the endometrium diagnosed as stage IIIA. The patient underwent surgery and chemotherapy and has been well with no evidence of disease for 20 months. The optimal treatment for this rare tumor has not been established. Considering its rarity and variability, it is difficult to establish an evidence-based therapeutic regimen.