Feeling the Burn: Intestinal Epithelial Cells Modify Their Lipid Metabolism in Response to Bacterial Fermentation Products.

Feeling the Burn: Intestinal Epithelial Cells Modify Their Lipid Metabolism in Response to Bacterial Fermentation Products.
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感觉灼烧感:肠上皮细胞响应细菌发酵产物改变其脂质代谢。

DOI:
10.1016/j.chom.2020.02.009
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发表时间:
2020
影响因子:
30.3
通讯作者:
Rawls,JohnF
Rawls,JohnF
中科院分区:
医学1区
文献类型:
--
作者:
Wen,Jia;Rawls,JohnF

文献摘要

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肠道上皮对膳食脂质的吸收是动物能量平衡和代谢健康的主要决定因素。最近的研究揭示了肠道微生物群在这一过程中的重要作用,但潜在的机制仍未得到解决。Araújo等人(2020)确定两种调节肠道脂质吸收和代谢的细菌发酵终产物。
Intestinal epithelial absorption of dietary lipids is a major determinant of animal energy balance and metabolic health. Recent studies uncovered significant roles for intestinal microbiota in this process, but underlying mechanisms remain unresolved. Araújo et al. (2020) identify two end-products of bacterial fermentation that regulate intestinal lipid absorption and metabolism.