Diabetic retinopathy in Joslin Clinic patients with adult-onset diabetes.
Diabetic retinopathy in Joslin Clinic patients with adult-onset diabetes.
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Joslin Clinic 成人发病糖尿病患者的糖尿病视网膜病变。
DOI：
10.1016/s0161-6420(81)34982-3
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发表时间：
1981
期刊：
影响因子：
13.7
通讯作者：
Sebestyen,JG
中科院分区：
文献类型：
--
作者：
Aiello,LM;Rand,LI;Briones,JC;Wafai,MZ;Sebestyen,JG
虽然只有一小部分成人发病的糖尿病患者会出现威胁视力的视网膜病变，但这一群体构成了寻求眼科治疗的糖尿病患者的主要部分。在乔斯林诊所的W.P.Beetham眼科有眼底照片的患者中，53%的人在20岁或以上患上糖尿病，近30%的患者在40岁或以上患糖尿病。在所有患有增殖性视网膜病变的患者中，22%属于后一组。在⩾40发作组中，54例增殖性视网膜病变患者中有10例未服用胰岛素。与年轻患者相比，年龄较大的患者发展为增殖性视网膜病变的患者在糖尿病病程较短、视力障碍较多后出现这种情况。黄斑水肿在成人患者中更为常见，在50岁以下的患者中出现黄斑水肿通常与增殖性或增殖性前期视网膜病变有关。
While only a small proportion of adult-onset diabetic patients develop vision threatening retinopathy, this group makes up a major portion of those diabetics seeking ophthalmologic care. Fifty-three percent of patients having fundus photographs at the W.P. Beetham Eye Unit of the Joslin Clinic developed diabetes at the age of 20 or over, and almost 30% at the age of 40 or over. Twenty-two percent of all patients seen with proliferative retinopathy were in this latter group. Ten of 54 patients with proliferative retinopathy in the ⩾40 onset group were not taking insulin. The older onset patients who developed proliferative retinopathy did so after shorter durations of diabetes and with more visual disability than younger onset patients. Macular edema was more common in adult-onset patients, and its presence in a patient less than 50 years old was usually associated with proliferative or preproliferative retinopathy.