Contribution of different bitter-sensitive taste cells to feeding inhibition in a caterpillar (Manduca sexta).
Contribution of different bitter-sensitive taste cells to feeding inhibition in a caterpillar (Manduca sexta).
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DOI：
10.1037//0735-7044.113.4.840
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发表时间：
1999-08
影响因子：
1.9
通讯作者：
J. Glendinning;Marci Tarre;Kiyoshi Asaoka
中科院分区：
文献类型：
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作者：
J. Glendinning;Marci Tarre;Kiyoshi Asaoka
许多对人类来说是苦味的化合物也会抑制昆虫的进食。毛虫（例如，Manduca sexta）用一些对味觉敏感的味觉细胞检测这些化合物。本研究探讨了这些味觉细胞在摄食抑制中的作用。行为学研究表明，3种苦味化合物（咖啡因、水杨苷和马兜铃酸）均能迅速抑制烟草天蛾的摄食。电生理学研究表明，每对苦味敏感的味觉细胞对苦味化合物的反应不同。消融研究表明，（a）对特定苦味化合物有强烈反应的味觉敏感细胞对足以抑制进食含有相同化合物的饮食，但（B）抑制进食不需要对味觉敏感细胞对。因此，不同对的味觉敏感的味觉细胞似乎对摄食抑制做出了部分冗余的贡献。
Many compounds that taste bitter to humans also inhibit feeding in insects. Caterpillars (e.g., Manduca sexta) detect these compounds with a few bitter-sensitive taste cells. This study examined the role of these taste cells in feeding inhibition. Behavioral studies demonstrated that 3 bitter compounds (caffeine, salicin, and aristolochic acid) all inhibited feeding rapidly in Manduca sexta. Electrophysiological studies revealed that each pair of bitter-sensitive taste cell differs in responsiveness to the bitter compounds. Ablation studies indicated that (a) those pairs of bitter-sensitive taste cells that responded vigorously to a particular bitter compound were sufficient to inhibit feeding on diets containing the same compound, but that (b) no pair of bitter-sensitive taste cells was necessary for inhibiting feeding. Thus, the different pairs of bitter-sensitive taste cells appear to make partially redundant contributions to feeding inhibition.