The Association of Cardiorespiratory Fitness and Physical Activity With Incidence of Hypertension in Men
The Association of Cardiorespiratory Fitness and Physical Activity With Incidence of Hypertension in Men
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DOI：
10.1038/ajh.2009.6
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发表时间：
2009-04-01
影响因子：
3.2
通讯作者：
Blair, Steven N.
中科院分区：
文献类型：
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作者：
Chase, Nancy L.;Sui, Xuemei;Blair, Steven N.
研究背景很少有前瞻性研究同时研究了体力活动、心肺功能（CRF）和初始血压正常个体高血压发展之间的关系。在有氧运动中心纵向研究（ACLS）中，我们研究了这种关联在最初健康的血压正常的男性之间。METHODS参与者是16,601名年龄在20-82岁的男性，他们在1970-2002年期间完成了基线检查，并随访了高血压发病率。体力活动是自我报告的，CRF是从最大跑步机测试的持续时间来量化的。在平均18年的随访中，共有2,346名男性报告了高血压。经年龄和检查年调整后，久坐、步行者/慢跑者/跑步者（WJR）和运动/健身等体力活动组的每10，000人年事件发生率分别为86.2、76.6和66.7，低、中和高CRF组分别为89.8、78.4和64.6（趋势P < 0.0001）。这些协会坚持进一步调整后的身体质量指数（BMI），吸烟，饮酒，静息收缩压，基线健康状况，疾病家族史，调查response patterns. CONCLUSION体力活动和CRF与发展高血压的风险较低，在一个分级的时尚。这些发现为卫生专业人员强调参加定期体育活动以改善男性高血压一级预防的重要性提供了依据。
BACKGROUNDFew prospective studies have simultaneously investigated the relationship between physical activity, cardiorespiratory fitness (CRF), and the development of hypertension in initially normotensive individuals. In the Aerobics Center Longitudinal Study (ACLS), we examined this association among initially healthy normotensive men.METHODSParticipants were 16,601 men aged 20-82 years who completed a baseline examination during 1970-2002 and were followed for hypertension incidence. Physical activity was self-reported and CRF was quantified from the duration of a maximal treadmill test.RESULTSA total of 2,346 men reported hypertension during a mean 18 years of follow-up. Event rates per 10,000 man-years adjusted for age and examination year were 86.2, 76.6, and 66.7 across physical activity groups of sedentary, walker/jogger/runner (WJR), and sport/fitness, respectively, and 89.8, 78.4, and 64.6 for low, middle, and high CRF, respectively (trend P < 0.0001). These associations persisted after further adjustment for body mass index (BMI), smoking, alcohol intake, resting systolic blood pressure, baseline health status, family history of diseases, and survey response patterns.CONCLUSIONBoth physical activity and CRF are associated with lower risk of developing hypertension in a graded fashion. These findings provide a basis for health professionals to emphasize the importance of participating in regular physical activity to improve fitness for the primary prevention of hypertension in men.