Development of relational reasoning during adolescence
Development of relational reasoning during adolescence
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DOI：
10.1111/j.1467-7687.2010.01014.x
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发表时间：
2010-11-01
影响因子：
3.7
通讯作者：
Blakemore, Sarah-Jayne
中科院分区：
文献类型：
--
作者：
Dumontheil, Iroise;Houlton, Rachael;Blakemore, Sarah-Jayne
据报道，在青少年发育期间，在各种认知任务中，行为和大脑活动发生了非线性变化。这些发育变化通常被解释为大脑结构变化的结果，包括青少年时期发生的灰质体积的非线性变化。然而，很少有研究试图将联合收割机的行为，功能和结构数据。这种多方法的方法是我们在目前的研究中采取的方法，该研究旨在研究关系推理过程中行为和大脑活动的发展变化，同时整合多种关系。我们使用了一个关系推理任务，已知的招募头外侧前额叶皮层（RLPFC），一个区域，在青春期经历了重大的结构变化。该任务是在行为（N = 178，7-27岁）和fMRI研究（N = 37，11-30岁）中对女性参与者进行的。观察到准确性的非线性变化，在青春期中期表现较差。fMRI和VBM结果揭示了一个复杂的图片的线性和可能的非线性变化与年龄。性能和结构的变化，部分原因是随着年龄的变化，RLPFC和内侧上级额回的活动，但不减少在前额叶/额盖之间的青春期中期和成年期的激活。这些功能变化可能反映了神经认知策略的成熟。
Non-linear changes in behaviour and in brain activity during adolescent development have been reported in a variety of cognitive tasks. These developmental changes are often interpreted as being a consequence of changes in brain structure, including non-linear changes in grey matter volumes, which occur during adolescence. However, very few studies have attempted to combine behavioural, functional and structural data. This multi-method approach is the one we took in the current study, which was designed to investigate developmental changes in behaviour and brain activity during relational reasoning, the simultaneous integration of multiple relations. We used a relational reasoning task known to recruit rostrolateral prefrontal cortex (RLPFC), a region that undergoes substantial structural changes during adolescence. The task was administered to female participants in a behavioural (N = 178, 7-27 years) and an fMRI study (N = 37, 11-30 years). Non-linear changes in accuracy were observed, with poorer performance during mid-adolescence. fMRI and VBM results revealed a complex picture of linear and possibly non-linear changes with age. Performance and structural changes partly accounted for changes with age in RLPFC and medial superior frontal gyrus activity but not for a decrease in activation in the anterior insula/frontal operculum between mid-adolescence and adulthood. These functional changes might instead reflect the maturation of neurocognitive strategies.