Active Surveillance in Papillary Thyroid Microcarcinomas is Feasible and Safe: Experience at a Single Italian Center
Active Surveillance in Papillary Thyroid Microcarcinomas is Feasible and Safe: Experience at a Single Italian Center
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DOI：
10.1210/clinem/dgz113
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发表时间：
2020-03-01
影响因子：
5.8
通讯作者：
Elisei, Rossella
中科院分区：
文献类型：
--
作者：
Molinaro, Eleonora;Campopiano, Maria Cristina;Elisei, Rossella
内容：在过去的30年中，甲状腺癌发病率的急剧上升主要归因于乳头状微小癌（mPTC）的诊断增加。目前的指南支持在适当选择的病例中采用观察性管理方法。目的：评估意大利mPTC主动监测的可行性，其对真实的生活的影响，并确定进展的风险因素。设计和设置：2014年，我们开始了一项mPTC患者主动监测的前瞻性观察性研究。患者：纳入的患者表现出单个Thy4或Thy5甲状腺结节，直径最大
Context: The dramatic rise in the incidence of thyroid cancer over the last 30 years is largely attributable to the increasing diagnosis of papillary microcarcinomas (mPTCs). Current guidelines endorse an observational management approach in properly selected cases.Objective: To evaluate the feasibility of active surveillance in mPTC in Italy, its impact on real life, and to identify risk factors of progression.Design and setting: In 2014 we started a prospective-observational study of active surveillance in mPTC patients.Patients: Included patients demonstrated a single Thy4 or Thy5 thyroid nodule, with largest diameter