Dynamic Assessment of Right Ventricular Volumes and Function by Real-Time Three-Dimensional Echocardiography: A Comparison Study With Magnetic Resonance Imaging in 100 Adult Patients
Dynamic Assessment of Right Ventricular Volumes and Function by Real-Time Three-Dimensional Echocardiography: A Comparison Study With Magnetic Resonance Imaging in 100 Adult Patients
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DOI：
10.1016/j.echo.2009.11.016
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发表时间：
2010-02-01
影响因子：
6.5
通讯作者：
Handke, Michael
中科院分区：
文献类型：
--
作者：
Leibundgut, Gregor;Rohner, Andreas;Handke, Michael
背景：本研究的目的是验证一种新的实时三维超声心动图(RT3DE)分析工具，用于测定未选定的成人患者的右室容量和功能。方法：连续100例右室正常或病理的成人患者纳入研究。使用专用的RT3DE软件生成右室的动态多面体模型。结果：RT3DE图像的舒张末、收缩末期和每搏输出量略低于磁共振(124.0±/-34.4vs134.2+/-39.2mL，P<；.001；65.2+/-23.5vs69.7+/-25.5mL，P=0.02；58.8+/-18.4vs64.5+/-24.1mL，P<；而射血分数无显著差异(47.8±8.5%比48.2±10.8%，P=.57)。经Bland-Altman相关分析，舒张末容量r=0.84(平均差值10.2mL；95%可信区间-31.3~51.7m L)，收缩末期容量r=0.83(平均差值4.5m L；95%CI-23.8~32.9 m L)，每搏量r=0.77(平均差值5.7 m L；95%C I-24.6~36.0 m L)，r=0.72(平均差值0.4%)；95%CI，-14.2%~15.1%)。结论：RT3DE成像评价右室容量和射血分数与MRI测量结果吻合较好。RT3DE成像在定量评价右室大小和功能方面可能成为MRI的一种省时、省钱的替代方法。(《美国社会超声心动图》2010；23：116-26。)
Background: The aim of this study was to validate a novel real-time three-dimensional echocardiographic (RT3DE) analysis tool for the determination of right ventricular volumes and function in unselected adult patients.Methods: A total of 100 consecutive adult patients with normal or pathologic right ventricles were enrolled in the study. A dynamic polyhedron model of the right ventricle was generated using dedicated RT3DE software. Volumes and ejection fractions were determined and compared with results obtained on magnetic resonance imaging (MRI) in 88 patients with adequate acquisitions.Results: End-diastolic, end-systolic, and stroke volumes were slightly lower on RT3DE imaging than on MRI (124.0 +/- 34.4 vs 134.2 +/- 39.2 mL, P < .001; 65.2 +/- 23.5 vs 69.7 +/- 25.5 mL, P = .02; and 58.8 +/- 18.4 vs 64.5 +/- 24.1 mL, P < .01, respectively), while no significant difference was observed for ejection fraction (47.8 +/- 8.5% vs 48.2 +/- 10.8%, P = .57). Correlation coefficients on Bland-Altman analysis were r = 0.84 (mean difference, 10.2 mL; 95% confidence interval [CI], -31.3 to 51.7 mL) for end-diastolic volume, r = 0.83 (mean difference, 4.5 mL; 95% CI, -23.8 to 32.9 mL) for end-systolic volume, r = 0.77 (mean difference, 5.7 mL; 95% CI, -24.6 to 36.0 mL) for stroke volume, and r = 0.72 (mean difference, 0.4%; 95% CI, -14.2% to 15.1%) for ejection fraction.Conclusion: Right ventricular volumes and ejection fractions as assessed using RT3DE imaging compare well with MRI measurements. RT3DE imaging may become a time-saving and cost-saving alternative to MRI for the quantitative assessment of right ventricular size and function. (J Am Soc Echocardiogr 2010;23:116-26.)