Harmonising the virological surveillance of influenza in Europe: results of an 18-country survey
Harmonising the virological surveillance of influenza in Europe: results of an 18-country survey
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DOI：
10.1016/j.virusres.2004.02.009
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发表时间：
2004-07-01
期刊：
影响因子：
5
通讯作者：
van der Velden, J
中科院分区：
文献类型：
--
作者：
Meerhoff, TJ;Paget, WJ;van der Velden, J
欧洲流感监测计划(EISS)以监测模式为基础，该模式结合了普通人群的临床和病毒学数据。欧洲18个国家每周向欧洲国际卫生组织(http://www.eiss.org).)报告流感活动向EISS成员发送了一份关于病毒学数据收集的调查问卷--电子盟友。这些问题包括样本采集、代表性、流感实验室诊断、变种报告、其他呼吸道感染检测、血清学检测、近患者检测和大流行准备。调查结果显示，流感的分型方法以聚合酶链式反应、酶联免疫吸附试验和血凝抑制法最为常见。对于流感的亚型，最常用的是HAI和PCR。在分型和分型中使用聚合酶链式反应(在西方使用更多的聚合酶链式反应)方面，出现了东西的分水岭。欧洲病毒学监测系统的差异可能会使直接比较变得困难，因为不同检测的检测率可能会有所不同。为了报告除流感以外的其他呼吸道感染，许多网络(68%)收集有关呼吸道合胞病毒的信息。这一点很重要，因为RSV引起的临床症状与流感相似，并可能在疾病负担方面产生类似的影响。随着RSV数据的收集，EISS正在向更广泛的病毒性呼吸道疾病转移。这项调查的结果将被用来更好地协调EISS的实验室方法，以便获得关于欧洲流感活动的更可靠和可比较的信息。(C)2004年，爱思唯尔出版。
The European influenza surveillance scheme (EISS) is based on a surveillance model that combines clinical and virological data in the general population. Eighteen countries in Europe report weekly influenza activity to EISS (http://www.eiss.org). A questionnaire on the virological data collection was sent-electronic ally to the EISS members. Questions on the specimen collection, representativity, laboratory diagnosis of influenza, reporting of variants, testing for other respiratory infections, serological testing, near-patient tests and preparedness for a pandemic were included. The results of the survey showed that for the typing of influenza, the methods polymerase chain reaction (PCR), enzyme-linked immunosorbent assay (ELISA) and haemagglutination inhibition (HAI) methods are used most frequently. For the subtyping of influenza, HAI and PCR are used most often. An east-west divide was seen for the use of PCR in typing and subtyping (more PCR use in the west). Differences in the virological surveillance systems in Europe can make direct comparisons difficult because detection rates may differ by test. For the reporting of other respiratory infections besides influenza, many networks (68%) collect information on RSV. This is important because RSV causes similar clinical symptoms as influenza and can have a similar impact in terms of burden of disease. With the collection of RSV data, EISS is moving to a broader spectrum of viral respiratory diseases. The findings of this survey will be used to better harmonise laboratory methods in EISS in order to obtain more reliable and comparable information on influenza activity in Europe. (C) 2004 Published by Elsevier B.V.