SIV mutations detected in morphine-treated Macaca mulatta following SIVmac239 infection.
SIV mutations detected in morphine-treated Macaca mulatta following SIVmac239 infection.
复制标题
SIVmac239 感染后经吗啡治疗的猕猴中检测到 SIV 突变。
DOI:
10.1007/978-1-4615-1951-5_24
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发表时间:
1995
影响因子:
--
通讯作者:
KillamJr,KF
中科院分区:
文献类型:
--
作者:
Chuang,RY;Chuang,LF;Li,Y;Kung,HF;KillamJr,KF
A study of eight SIVmac239-infected rhesus monkeys revealed that morphine treatment altered the progression of viremia, the rate of virus growth, and the behavioral pattern of the infected animals (1,2). Studies of SIVmac-infected tissue culture cells (CEM x174) also indicated that morphine stimulates the replication of SIVmac by preventing an early lysis of the cells (3). The present study describes the molecular genetics of SIVmac isolated from one of the morphine-treated, SIVmac239-infected monkeys.