SIV mutations detected in morphine-treated Macaca mulatta following SIVmac239 infection.

SIV mutations detected in morphine-treated Macaca mulatta following SIVmac239 infection.
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SIVmac239 感染后经吗啡治疗的猕猴中检测到 SIV 突变。

DOI:
10.1007/978-1-4615-1951-5_24
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发表时间:
1995
影响因子:
--
通讯作者:
KillamJr,KF
KillamJr,KF
中科院分区:
医学4区
文献类型:
--
作者:
Chuang,RY;Chuang,LF;Li,Y;Kung,HF;KillamJr,KF

文献摘要

被引文献

相似文献

一项对8只感染sivmac239的恒河猴的研究表明,吗啡治疗改变了病毒血症的进展、病毒的生长速度和感染动物的行为模式(1,2)。对SIVmac感染的组织培养细胞(CEM x174)的研究也表明,吗啡通过阻止细胞的早期裂解来刺激SIVmac的复制(3)。本研究描述了从吗啡治疗的sivmac239感染猴子中分离的SIVmac的分子遗传学。
A study of eight SIVmac239-infected rhesus monkeys revealed that morphine treatment altered the progression of viremia, the rate of virus growth, and the behavioral pattern of the infected animals (1,2). Studies of SIVmac-infected tissue culture cells (CEM x174) also indicated that morphine stimulates the replication of SIVmac by preventing an early lysis of the cells (3). The present study describes the molecular genetics of SIVmac isolated from one of the morphine-treated, SIVmac239-infected monkeys.