Latex rubber condoms: Predicting and extending shelf life
Latex rubber condoms: Predicting and extending shelf life
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DOI：
10.1016/0010-7824(96)00041-8
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发表时间：
1996-04-01
期刊：
影响因子：
2.9
通讯作者：
Marlowe, DE
中科院分区：
文献类型：
--
作者：
Free, MJ;Srisamang, V;Marlowe, DE
来自五个制造商的避孕套在五个国家受到受控的热、湿度和空气暴露以及不同的自然环境的影响。在有氧条件下（渗透性包装或未包装的避孕套），压力特性下降。下降率与温度之间的关系是二次关系。在平均储存温度为 30 摄氏度及以下的限氧条件（铝箔包裹的包装）下，应变性能下降，而应力性能变化很小或没有显着变化。其效果是使避孕套变得更硬；使用中的高破损率与产品变硬有关。提出了预测避孕套货架稳定性的加速老化测试的新原理，包括控制避孕套变硬趋势的测试。硅胶润滑剂、不渗透包装以及在避孕套配方中添加抗氧化剂可以防止或最大程度地减少乳胶避孕套的有氧分解。使用低模量的避孕套可以防止过度僵硬。
Condoms from five manufacturers were subjected to controlled exposures of heat, humidity, and air and to different natural environments in five countries. Under aerobic conditions (condoms in permeable packages or unpackaged), stress properties declined. The relationship between rate of decline as a function of temperature was quadratic. Under oxygen-restricted conditions (foil-wrapped packages) at average storage temperatures of 30 degrees C and lower, strain properties declined with Little or no significant change in stress properties. The effect is to cause condoms to become stiffer; high-breakage rates in use have been correlated with product stiffening. A new rationale for accelerated-aging tests to predict condom shelf stability is suggested, including a test to control the trend of condoms to stiffen. Silicone lubricant, impermeable packaging, and inclusion of antioxidants in the condom formulation can prevent or minimize aerobic breakdown of latex condoms. Specifying low-modulus condoms can prevent excessive stiffening.