Control of the architectural assembly of octacalcium phosphate crystals in denatured collagenous matrices
Control of the architectural assembly of octacalcium phosphate crystals in denatured collagenous matrices
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DOI：
10.1039/a906271h
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发表时间：
2000-02-01
影响因子：
--
通讯作者：
Ripamonti, A
中科院分区：
文献类型：
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作者：
Falini, G;Gazzano, M;Ripamonti, A
通过蒸发明胶水溶液获得的干凝胶被用作磷酸钙晶体组装体生长的模板。通过将钙离子和磷酸根离子的溶液从相对两端扩散到明胶膜中，在明胶干凝胶内生长磷酸八钙（OCP）晶体。用光学显微镜、扫描电镜和X射线衍射研究了明胶薄膜表面和内部生长的晶体的结构、形貌和取向。OCP是唯一可检测的结晶相。晶体优先生长为沿沿着其c轴伸长的薄板，其大{100}面平行于明胶薄膜片。当明胶薄膜发生单轴形变时，OCP晶体的c轴几乎平行于形变方向生长。根据模板成核机制，提出了OCP在三螺旋胶原分子上有序生长的结构模型。
Xerogels, obtained by evaporating a water solution of gelatin, were used as templates for the growth of crystal assemblies of calcium phosphate. Octacalcium phosphate (OCP) crystals were grown inside the gelatin xerogel by diffusion of solutions of calcium and phosphate ions into the gelatin films from opposite ends. The structure, morphology and orientation of the crystals grown on the surfaces and inside the gelatin films were studied by optical and scanning electron microscopy and X-ray diffraction. OCP was the unique detectable crystalline phase. The crystals preferentially grew as thin plates elongated along their c axes with large {100} faces parallel to the sheets of gelatin films. When the gelatin films were uniaxially deformed the OCP crystals grew with their c axes almost parallel to the direction of deformation. According to a mechanism of templated nucleation, a structural model for the ordered growth of OCP on the portions of triple helical collagen molecules has been proposed.