No Linear Association Between Number of Concussions or Years Played and Cognitive Outcomes in Retired NFL Players
No Linear Association Between Number of Concussions or Years Played and Cognitive Outcomes in Retired NFL Players
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DOI：
10.1093/arclin/acz008
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发表时间：
2020-05-01
影响因子：
2.6
通讯作者：
Cullum, C. Munro
中科院分区：
文献类型：
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作者：
Fields, Lindy;Didehbani, Nyaz;Cullum, C. Munro
目的：探讨国家橄榄球联盟(NFL)退役球员的脑震荡病史和打球年限是否与认知结果呈线性相关。方法：对35名50岁以上至少经历过一次脑震荡的NFL退役球员进行临床访谈和简明的神经心理测试。相关分析在暴露变量[脑震荡总次数、脑震荡伴意识丧失(LOC)和玩耍年限]与认知表现之间进行了相关分析，认知表现以神经心理测量的表现(注意力/处理速度、语言、记忆和总体合成分数)为基础。结果：经多次比较校正的相关分析未显示暴露变量与认知结果之间有任何统计学意义的相关性。结论：我们没有发现认知结果与总脑震荡次数、伴LOC的脑震荡或在NFL踢球的年限之间存在显著的线性关系。这些发现不支持与运动相关的头部撞击暴露与以后生活中的认知结果之间的剂量-反应关系。相反，研究结果表明，一些退役球员在晚年经历的认知困难与整个足球生涯中遭受的头部撞击并不是直接线性相关的，而是与尚未阐明的因素或因素组合有关。
Objective: The aim of the current study is to examine whether concussion history and years played are linearly associated with cognitive outcomes in retired National Football League (NFL) players.Method: Thirty-five retired NFL players over the age of 50 who had sustained at least one concussion completed a clinical interview and brief neuropsychological battery. Correlational analyses were conducted between exposure variables [number of total concussions, concussions with loss of consciousness (LOC), and years played] and cognitive performance as characterized by cognitive composite scores based on performance on neuropsychological measures (attention/processing speed, language, memory, and overall composite scores).Results: Correlational analyses corrected for multiple comparisons did not reveal any statistically significant correlations between exposure variables and cognitive outcomes.Conclusions: We did not find a significant linear association between cognitive outcomes and either number of total concussions, concussions with LOC, or years played in the NFL. These findings do not support a dose-response relationship between sports-related exposure to head impacts and cognitive outcomes later in life. Rather, the findings suggest that cognitive difficulties experienced by some retired players later in life are not directly linearly associated with quantified exposure to head impacts sustained throughout a football career, but related to factors or combinations of factors that have yet to be elucidated.