Incidence of the major stroke subtypes - Initial findings from the North East Melbourne Stroke Incidence Study (NEMESIS)
Incidence of the major stroke subtypes - Initial findings from the North East Melbourne Stroke Incidence Study (NEMESIS)
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DOI：
10.1161/01.str.32.8.1732
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发表时间：
2001-08-01
期刊：
影响因子：
8.3
通讯作者：
Donnan, GA
中科院分区：
文献类型：
--
作者：
Thrift, AG;Dewey, HM;Donnan, GA
背景和目的--基于人群的卒中发病率研究是确定特定社会中卒中发生数量的唯一准确方法。由于主要的卒中亚型具有不同的发病率和结局模式，因此有关卒中亚型自然史的信息至关重要。本研究的目的是确定墨尔本地区主要卒中亚型的发病率和病死率。方法：在1996年和1997年的12个月期间，对澳大利亚墨尔本北部和东部郊区的133816名居民中发生的所有疑似中风进行鉴定和评估。多个重叠的来源被用来确定病例，并使用中风和病死率的标准。中风亚型的定义，CT，MRI，和autoscopy.Results-three 81中风发生在353人在研究期间，与276（72%）是首次在一生中中风。其中，72.5%（95% CI 67.2%至77.7%）为脑梗死，14.5%（95% CI 10.3%至18.6%）为脑出血，4.3%（95% CI 1.9%至6.8%）为蛛网膜下腔出血，8.7%（95% CI 5.4%至12.0%）为未确定类型的卒中。脑梗死的28天病死率为12%（95%CI 7%~ 16%）。百分之四十五（95% CI 30%至60%）脑出血，50%（95%CI 22%至78%）为蛛网膜下腔出血，和38%（95%CI 18%至57%）为中风的未确定type. Conclusions中风亚型和28天病死率的总体分布没有显着不同，从大多数欧洲国家或美国。然而，澳大利亚境内亚型的发病率可能存在一些差异。
Background and Purpose-Population-based stroke incidence studies are the only accurate way to determine the number of strokes that occur in a given society. Because the major stroke subtypes have different patterns of incidence and outcome, information on the natural history of stroke subtypes is essential. The purpose of the present study was to determine the incidence and case-fatality rate of the major stroke subtypes in a geographically defined region of Melbourne. Australia.Methods-All suspected strokes that occurred among 133 816 residents of suburbs north and east of Melbourne, Australia, during a 12-month period of 1996 and 1997 were identified and assessed. Multiple overlapping sources were used to ascertain cases, and standard criteria for stroke and case-fatality were used. Stroke subtypes were defined by CT, MRI, and autopsy.Results-Three hundred eighty-one strokes occurred among 353 persons during the study period, with 276 (72%) being first-ever-in-a-lifetime strokes. Of these, 72.5% (95% Cl 67.2% to 77.7%) were cerebral infarction, 14.5% (95% CI 10.3% to 18.6%) were intracerebral hemorrhage, 4.3% (95% CI 1.9% to 6.8%) were subarachnoid hemorrhage, and 8.7% (95% Cl 5.4% to 12.0%) were stroke of undetermined type. The 28-day case-fatality rate was 12% (95% Cl 7% to 16%) for cerebral infarction. 45% (95% Cl 30% to 60%) for intracerebral hemorrhage, 50% (95% Cl 22% to 78%) for subarachnoid hemorrhage, and 38% (95% Cl 18% to 57%) for stroke of undetermined type.Conclusions-The overall distribution of stroke subtypes and 28-day case-fatality rates are not significantly different from those of most European countries or the United States. There may, however, be some differences in the incidence of subtypes within Australia.