Gender Considerations in Addiction: Implications for Treatment.
Gender Considerations in Addiction: Implications for Treatment.
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DOI：
10.1007/s40501-015-0054-5
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发表时间：
2015-09
影响因子：
--
通讯作者：
Svikis DS
中科院分区：
文献类型：
--
作者：
Polak K;Haug NA;Drachenberg HE;Svikis DS
意见陈述物质使用障碍（SUD）的个体是异质性的，使综合评估成为治疗计划的重要组成部分。由于有各种药物和心理社会治疗方法，必须考虑到患者的需要和特点，以及针对具体物质的治疗选择。特别是，临床医生在提出治疗建议时，应考虑患者的性别以及激素和其他生物因素。女性面临着更大的风险，各种医疗和心理社会后果，并可能受益于药理学和/或行为疗法，不同于那些最有益于男性。怀孕和性别认同也值得特别考虑。临床医生必须随时了解新的研究结果，这些研究结果可以指导针对SUD男性和女性的循证治疗。展望未来，药物基因组学领域为确定特定SUD患者的最有效药物治疗提供了额外的承诺。
Opinion statementIndividuals with substance use disorders (SUD) are heterogeneous, making comprehensive assessment an essential part of treatment planning. Since a variety of pharmacological and psychosocial treatments are available, patient needs and characteristics, as well as substance-specific treatment options must be taken into account. In particular, clinicians should consider patient gender, as well as hormonal and other biological factors, when making treatment recommendations. Women are at greater risk for a variety of medical and psychosocial consequences, and may benefit from pharmacological and/or behavioral therapies that differ from those most beneficial for men. Pregnancy and gender identity also warrant special consideration. It is imperative that clinicians keep informed about new research findings that can guide tailoring of evidence-based treatments for men and women with SUD. Looking ahead, the field of pharmacogenomics offers additional promise for identifying the most effective pharmacotherapies for specific patients with SUD.