Muscle fat infiltration following whiplash: A computed tomography and magnetic resonance imaging comparison
Muscle fat infiltration following whiplash: A computed tomography and magnetic resonance imaging comparison
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DOI：
10.1371/journal.pone.0234061
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发表时间：
2020-06-02
期刊：
影响因子：
3.7
通讯作者：
Parrish, Todd B.
中科院分区：
文献类型：
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作者：
Elliott, James M.;Smith, Andrew C.;Parrish, Todd B.
在这里，我们提出了一个次要的分析，从父母的数据库97急性受伤的参与者参加了一个前瞻性的初始队列研究的挥鞭样损伤恢复后，机动车碰撞（MVC）。本研究旨在通过围创伤期计算机断层扫描（CT）和磁共振成像（MRI）纵向测量，研究不同程度挥鞭样损伤相关残疾的受试者的深颈和浅颈伸肌。36名患者在1级创伤指定急诊科接受了颈椎CT标准护理成像。所有36名参与者在受伤后< 1周、2周、3个月和12个月进行颈椎MRI评估，并根据初始疼痛严重程度和颈部残疾指数的百分比评分（恢复（NDI为0-8%）、轻度（NDI为10-28%）或重度（NDI为10-28%））分为三组。30%））。MVC后1周，CT肌肉衰减值与MRI上的肌肉脂肪浸润（MFI）显著相关。在入组时，各组之间的肌肉衰减没有显著差异。在严重组中观察到深层肌肉衰减低于浅层伸肌的趋势。MVC后1年时，重度组MRI上深部肌肉的MFI值显著高于轻度组。这项研究提供了进一步的证据，表明1）深部MFI的幅度对于那些有风险并最终过渡到慢性WAD的人来说是独特的，2）通过CT肌肉衰减确定的创伤前或创伤周围的肌肉健康可能有助于我们对长期恢复的理解。
Here we present a secondary analysis from a parent database of 97 acutely injured participants enrolled in a prospective inception cohort study of whiplash recovery after motor vehicle collision (MVC). The purpose was to investigate the deep and superficial neck extensor muscles with peri-traumatic computed tomography (CT) and longitudinal measures of magnetic resonance imaging (MRI) in participants with varying levels of whiplash-related disability. Thirty-six underwent standard care imaging of the cervical spine with CT at a level-1 trauma designated emergency department. All 36 participants were assessed with MRI of the cervical spine at < 1-week, 2-weeks, 3-, and 12-months post-injury and classified into three groups using initial pain severity and percentage scores on the Neck Disability Index (recovered (NDI of 0-8%), mild (NDI of 10-28%), or severe (NDI. 30%)) at 3-months post MVC. CT muscle attenuation values were significantly correlated to muscle fat infiltration (MFI) on MRI at one-week post MVC. There was no significant difference in muscle attenuation across groups at the time of enrollment. A trend of lower muscle attenuation in the deep compared to the superficial extensors was observed in the severe group. MFI values in the deep muscles on MRI were significantly higher in the severe group when compared to the mild group at 1-year post MVC. This study provides further evidence that the magnitude of 1) deep MFI appears unique to those at risk of and eventually transitioning to chronic WAD and that 2) pre- or peri-traumatic muscular health, determined by CT muscle attenuation, may be contribute to our understanding of long-term recovery.