Information transfer rate of nonspiking afferent neurons in the crab
Information transfer rate of nonspiking afferent neurons in the crab
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DOI：
10.1152/jn.01176.2003
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发表时间：
2004-07-01
影响因子：
2.5
通讯作者：
DiCaprio, RA
中科院分区：
文献类型：
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作者：
DiCaprio, RA
胸髋肌感受器（TCMRO）是蟹腿胸髋关节上唯一的本体感受器。TCMRO的S和T传入神经元仅通过膜电位的分级变化向CNS传递信号。这些传入的信息传递速率通过测量这些细胞在用相同的随机运动序列重复刺激受体后的信噪比（SNR）并应用香农公式计算高斯通道的信息容量来确定。细胞内记录从邻近受体起点处的转导位点的S和T传入神经和沿该位点远端5 - 7 mm的轴突沿着进行。这些非尖峰传入神经抑制受体运动，并以极高的保真度传递信息。在200 Hz刺激带宽的大部分范围内，转导部位附近的两个神经元的SNR> 1000，平均信息传输速率类似于2，500比特/秒。当在500 Hz的较宽带宽上计算时，信息速率> 4，600 bits/s。轴突电缆特性对信息速率的影响通过确定来自转导区域远端5 - 7 mm处的膜电位记录的SNR来评估。沿着轴突分级传输的主要影响是感觉信号的衰减和低通滤波。随之而来的信号功率和带宽的减少使信息传输在200 Hz上减少了10 - 15%，在500 Hz带宽上减少了30%。
The thoracic-coxal muscle receptor organ (TCMRO) is the only proprioceptor at the thoracic-coxal joint in the crab leg. The S and T afferent neurons of the TCMRO convey signals to the CNS solely by means of graded changes in membrane potential. The rate of information transfer of these afferents was determined by measuring the signal-to-noise ratio ( SNR) of these cells after repeated stimulation of the receptor with identical sequences of random movement and applying the Shannon formula for the information capacity of a Gaussian channel. Intracellular recordings were made from the S and T afferents adjacent to the transduction site at the origin of the receptor and along the axon 5 - 7 mm distal to this site. These nonspiking afferents transduce receptor movement and transmit this information with extremely high fidelity. The SNR of both neurons near the transduction site was > 1000 over most of the 200 Hz stimulation bandwidth, and the mean information transfer rate was similar to 2,500 bits/s. When calculated over a wider bandwidth of 500 Hz, the information rate was > 4,600 bits/s. The effect of axonal cable properties on the information rate was evaluated by determining the SNR from membrane potential recordings made 5 - 7 mm distal to the transduction region. The major effect of graded transmission along the axon was attenuation and low- pass filtering of the sensory signal. The consequent reduction in signal power and bandwidth decreased the information transfer by similar to 10 - 15% over 200 Hz and similar to 30% over a 500 Hz bandwidth.