Advances in Pediatric Fatty Liver Disease Pathogenesis, Diagnosis, and Treatment
Advances in Pediatric Fatty Liver Disease Pathogenesis, Diagnosis, and Treatment
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DOI：
10.1016/j.gtc.2018.07.016
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发表时间：
2018-12-01
影响因子：
3.7
通讯作者：
Vos, Miriam B.
中科院分区：
文献类型：
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作者：
Braun, Hayley A.;Faasse, Sarah A.;Vos, Miriam B.
儿童非酒精性脂肪肝是一种日益流行的疾病，但其病理生理学尚未完全阐明，诊断困难且具有侵入性，治疗选择有限。本文讨论了最近在了解非酒精性脂肪肝的病理生理学方面取得的进展，微创诊断方法的发展，以及新兴的治疗方案，包括正在进行的儿童临床试验。
Pediatric nonalcoholic fatty liver disease is an increasingly prevalent disease, but its pathophysiology is not fully elucidated, diagnosis is difficult and invasive, and therapeutic options are limited. This article addresses the recent advancements made in understanding the pathophysiology of nonalcoholic fatty liver disease, the development of less invasive diagnostic modalities, and emerging therapeutic options, including ongoing clinical trials in children.