Influence of Malnutrition on the Concentration of IgA, Lysozyme, Amylase, and Aminopeptidase in Children's Tears 1
Influence of Malnutrition on the Concentration of IgA, Lysozyme, Amylase, and Aminopeptidase in Children's Tears 1
复制标题
营养不良对儿童泪液中IgA、溶菌酶、淀粉酶、氨肽酶浓度的影响1
DOI：
10.3181/00379727-157-40024
复制
发表时间：
1978
影响因子：
--
通讯作者：
D. Mcmurray
中科院分区：
文献类型：
--
作者：
Ronald R. Watson;M. Reyes;D. Mcmurray
对哥伦比亚贫困城市人口的64名学龄前儿童进行了研究，以确定中度至重度营养不良对血清和泪液中几种蛋白质的影响。分泌型伊加，溶菌酶和淀粉酶被发现在显着降低浓度的眼泪营养不良的儿童。营养状况对总蛋白、白蛋白和氨肽酶无影响。在血清中，伊加浓度显着较高的最营养不良组，而总蛋白和白蛋白减少。这些数据表明，在营养不良的儿童粘膜表面感染的易感性增加可能是由于分泌物中的保护性物质，如伊加和溶菌酶的浓度降低。
Summary Sixty-four pre-school-age children from a poor urban population in Colombia were studied to determine the influence of moderate to severe malnutrition on several proteins in the serum and tears. Secretory IgA, lysozyme, and amylase were found in significantly reduced concentrations in the tears of malnourished children. No influence of nutritional status on total proteins, albumin, and aminopeptidase was observed in this secretion. In the serum, IgA concentrations were significantly higher in the most malnourished group, while total proteins and albumin were reduced. These data suggest that increased susceptibility to infections of mucosal surfaces in malnourished children may be due to reduced concentrations of protective substances such as IgA and lysozyme in secretions.