Estimating neonatal length of stay for babies born very preterm
Estimating neonatal length of stay for babies born very preterm
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DOI：
10.1136/archdischild-2017-314405
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发表时间：
2019-03-01
影响因子：
4.4
通讯作者：
Millman, Guy
中科院分区：
文献类型：
--
作者：
Seaton, Sarah E.;Barker, Lisa;Millman, Guy
目的 预测所有入院的极早产单胎婴儿在新生儿护理中的住院时间。设置英格兰所有新生儿病房。患者为 2011 年至 2014 年胎龄 24-31 周出生的单胎婴儿。数据来自国家新生儿研究数据库。方法采用竞争风险方法来调查新生儿护理中死亡或从新生儿病房出院的竞争结果。一个事件的发生会阻止另一事件的发生。这种方法可用于估计随时间变化的存活婴儿或已出院婴儿的百分比。结果 总共纳入了 20 571 名极早产婴儿。在竞争风险模型中，胎龄被调整为随时间变化的协变量，从而允许胎龄周数之间的差异随时间变化。估计死亡或从新生儿病房出院的预测百分比，并按孕周以图形方式呈现。根据这些百分比，可以根据出生后的天数和出院时的校正胎龄来估计住院时间。 结论 这些结果可用于向父母提供有关住院时间和死亡风险的咨询。
Objective To predict length of stay in neonatal care for all admissions of very preterm singleton babies.Setting All neonatal units in England.Patients Singleton babies born at 24-31 weeks gestational age from 2011 to 2014. Data were extracted from the National Neonatal Research Database.Methods Competing risks methods were used to investigate the competing outcomes of death in neonatal care or discharge from the neonatal unit. The occurrence of one event prevents the other from occurring. This approach can be used to estimate the percentage of babies alive, or who have been discharged, over time.Results A total of 20 571 very preterm babies were included. In the competing risks model, gestational age was adjusted for as a time-varying covariate, allowing the difference between weeks of gestational age to vary over time. The predicted percentage of death or discharge from the neonatal unit were estimated and presented graphically by week of gestational age. From these percentages, estimates of length of stay are provided as the number of days following birth and corrected gestational age at discharge.Conclusions These results can be used in the counselling of parents about length of stay and the risk of mortality.