INITIATION OF LIMB BUD OUTGROWTH IN EMBRYONIC CHICK
INITIATION OF LIMB BUD OUTGROWTH IN EMBRYONIC CHICK
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DOI：
10.1016/0012-1606(71)90095-9
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发表时间：
1971-01-01
影响因子：
2.7
通讯作者：
JANNERS, MY
中科院分区：
文献类型：
--
作者：
SEARLS, RL;JANNERS, MY
通过测定翅膀区域和侧翼区域标记指数的变化，研究了胚胎雏鸡翅膀发育过程中细胞分裂率的变化。结果表明，在第16 ~ 20阶段，翼区标记指数变化不大，而翼区标记指数在同一时期急剧下降。侧翼区域标记指数的下降是由于该区域的增殖指数从16期的100%变化到19期的75%。侧翼增殖指数的变化不能轻易地与侧翼的分化变化相关联，但与形态变化密切相关。
Changes in the rate of cell division that occur during the initiation of outgrowth of the embryonic chick wing have been investigated by determination of changes in the labeling index in the wing region and the flank region. It has been found that the labeling index changes very little in the wing region between stage 16 and stage 20, but decreases rapidly in the flank region during the same period. The decrease in labeling index in the flank region results from a change in the proliferative index in that region from 100% at stage 16 to 75% at stage 19. This change in the proliferative index in the flank cannot be easily correlated with differentiative changes in the flank, but correlates very well with morphological changes.