Direct visualisation of micelles of Pluronic block copolymers in aqueous solution by cryo-TEM
Direct visualisation of micelles of Pluronic block copolymers in aqueous solution by cryo-TEM
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DOI：
10.1039/a902369k
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发表时间：
1999-07-15
影响因子：
3.3
通讯作者：
Goldbeck-Wood, G
中科院分区：
文献类型：
--
作者：
Lam, YM;Grigorieff, N;Goldbeck-Wood, G
用低温透射电子显微镜观察了(环氧乙烷)(环氧丙烷)(环氧乙烷)三嵌段共聚物(Pluronic F127和L64)在水溶液中形成的胶束。实现的分辨率允许详细检查单个胶束、其大小、形状、核壳结构以及长程有序。报告了微观结构与溶液浓度以及Pluronic聚合物类型(嵌段大小)的关系，并证明了该方法对这些参数的敏感性。
Micelles formed by (ethylene oxide) (propylene oxide) (ethylene oxide) triblock copolymers (Pluronic F127 and L64) in aqueous solutions have been visualised by cryogenic transmission electron microscopy (cryo-TEM). The resolution achieved allows detailed inspection of the individual micelles, their size, shape, core-shell structure as well as long-range order. The dependence of the microstructure on the concentration of the solution as well as on the type (block sizes) of the Pluronic polymer are reported and demonstrate the sensitivity of the method to these parameters.