Dietary intake and the development of the metabolic syndrome - The Atherosclerosis Risk in Communities study
Dietary intake and the development of the metabolic syndrome - The Atherosclerosis Risk in Communities study
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DOI：
10.1161/circulationaha.107.716159
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发表时间：
2008-02-12
期刊：
影响因子：
37.8
通讯作者：
Stevens, June
中科院分区：
文献类型：
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作者：
Lutsey, Pamela L.;Steffen, Lyn M.;Stevens, June
背景-饮食在代谢综合征（MetSyn）起源中的作用尚不清楚;因此，我们试图利用9514名参与者的前瞻性数据来评估MetSyn事件与饮食摄入之间的关系方法和结果-通过66项食物频率问卷在基线评估饮食摄入。我们使用主成分分析从32个食物组中得出“西方”和“谨慎”的饮食模式，并评估了ARIC队列先前研究中使用的10个食物组。MetSyn由美国心脏协会指南定义。使用比例风险回归。在9年的随访中，确定了3782例MetSyn事件病例。在调整人口统计学因素、吸烟、体力活动和能量摄入后，西方饮食模式的消费（P（趋势）= 0.03）与MetSyn事件呈负相关。在进一步调整肉类、乳制品、水果和蔬菜、精制谷物和全谷物的摄入量后，对单个食物组的分析显示，肉类（Ptrend < 0.001）、油炸食品（Ptrend = 0.02）和无糖苏打水（Ptrend = < 0.001）也与MetSyn事件呈不利相关，而乳制品消费（Ptrend = 0.006）是有益的。没有协会之间观察到事件MetSyn和谨慎的饮食模式或摄入量的全谷物，精制谷物，水果和蔬菜，坚果，咖啡，或甜beverage. Conclusions这些前瞻性的研究结果表明，消费西方的饮食模式，肉类，油炸食品促进MetSyn的发病率，而乳制品消费提供了一些保护。无糖汽水协会没有假设，值得进一步研究。
Background-The role of diet in the origin of metabolic syndrome (MetSyn) is not well understood; thus, we sought to evaluate the relationship between incident MetSyn and dietary intake using prospective data from 9514 participants (age, 45 to 64 years) enrolled in the Atherosclerosis Risk in Communities (ARIC) study.Methods and Results-Dietary intake was assessed at baseline via a 66-item food frequency questionnaire. We used principal-components analysis to derive "Western" and "prudent" dietary patterns from 32 food groups and evaluated 10 food groups used in previous studies of the ARIC cohort. MetSyn was defined by American Heart Association guidelines. Proportional-hazards regression was used. Over 9 years of follow-up, 3782 incident cases of MetSyn were identified. After adjustment for demographic factors, smoking, physical activity, and energy intake, consumption of a Western dietary pattern (P(trend) = 0.03) was adversely associated with incident MetSyn. After further adjustment for intake of meat, dairy, fruits and vegetables, refined grains, and whole grains, analysis of individual food groups revealed that meat (Ptrend < 0.001), fried foods (Ptrend = 0.02), and diet soda (Ptrend = < 0.001) also were adversely associated with incident MetSyn, whereas dairy consumption (Ptrend = 0.006) was beneficial. No associations were observed between incident MetSyn and a prudent dietary pattern or intakes of whole grains, refined grains, fruits and vegetables, nuts, coffee, or sweetened beverages.Conclusions-These prospective findings suggest that consumption of a Western dietary pattern, meat, and fried foods promotes the incidence of MetSyn, whereas dairy consumption provides some protection. The diet soda association was not hypothesized and deserves further study.