Balancing control and simplicity: A variable aggregation method in intensity modulated radiation therapy planning.
Balancing control and simplicity: A variable aggregation method in intensity modulated radiation therapy planning.
复制标题
平衡控制和简单性：调强放射治疗计划中的可变聚合方法。
DOI：
10.1016/j.laa.2007.11.010
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发表时间：
2008
影响因子：
1.1
通讯作者：
Küfer,Karl-Heinz
中科院分区：
文献类型：
--
作者：
Süss,Philipp;Küfer,Karl-Heinz
人们普遍认为，并非所有自由度都需要为调强放射治疗 (IMRT) 中的治疗计划问题提供良好的解决方案。然而，利用这一事实的典型方法要么增加优化问题的复杂性，要么本质上是启发式的。在这项工作中，我们引入了一种基于自适应细化变量簇的技术，以连续获得更好的治疗计划。该方法基于较小的模型创建近似解，这些模型可能任意接近最优解。尽管使用特定的治疗计划模型来说明该方法，但构成变量聚类和自适应细化的组件独立于特定的优化问题。
It is commonly believed that not all degrees of freedom are needed to produce good solutions for the treatment planning problem in intensity modulated radiation therapy (IMRT). However, typical methods to exploit this fact either increase the complexity of the optimization problem or are heuristic in nature. In this work we introduce a technique based on adaptively refining variable clusters to successively attain better treatment plans. The approach creates approximate solutions based on smaller models that may come arbitrarily close to the optimal solution. Although the method is illustrated using a specific treatment planning model, the components constituting the variable clustering and the adaptive refinement are independent of the particular optimization problem.