The incidentally discovered adrenal mass.
The incidentally discovered adrenal mass.
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DOI：
10.1056/nejmc070612
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发表时间：
2007-05
期刊：
影响因子：
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通讯作者：
K. Pacak;G. Eisenhofer;A. Grossman
中科院分区：
文献类型：
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作者：
K. Pacak;G. Eisenhofer;A. Grossman
2. Herrera MF，Grant CS，货车Heerden JA，Sheedy PF，Ilstrup DM.偶然发现的肾上腺肿瘤：一个机构的观点。外科1991; 110（6）：10141021。审查/CIMDx 342例患者研究偶发肾上腺肿块大小对无已知恶性肿瘤患者的影响。在172名患者（50%）中进行了评价生化功能亢进的研究，发现其中2名患者患有皮质醇生成肿瘤和5名嗜铬细胞瘤。55例患者在肾上腺切除术时获得了组织学诊断证据。在五名患者中发现了恶性肿瘤（四名原发性和一名转移性），最小的恶性肿瘤测量为5 cm。在287例无组织学诊断的患者中，251例（88%）进行了至少1年的临床随访，其中156例（54%）进行了重复CT扫描。这些患者均无临床或生化肾上腺异常。作者建议对所有> 4 cm的病变进行生化筛查和手术切除。<4cm的病灶应在3个月时进行随访CT检查。4
2. Herrera MF, Grant CS, van Heerden JA, Sheedy PF, Ilstrup DM. Incidentally discovered adrenal tumors: an institutional perspective. Surgery 1991; 110(6):10141021. Review/OtherDx 342 patients To investigate the effect of size of incidental adrenal masses in patients without known malignancy. Studies to evaluate biochemical hyperfunction were performed in 172 patients (50%), 2 of whom were found to have cortisol-producing tumors and 5 pheochromocytomas. Histologic proof of diagnosis was obtained in 55 patients at the time of adrenalectomy. Malignancy was discovered in five patients (four primary and one metastatic), the smallest malignant tumor measuring 5 cm. In the 287 patients without histologic diagnoses, a minimum of 1 year of clinical follow-up was obtained in 251 (88%), including repeat CT scan in 156 (54%). None of these patients had clinical or biochemical adrenal abnormalitie. Authors suggest biochemical screening and surgical excision for all lesions >4 cm. Follow-up CT should be performed at 3 months in lesions <4 cm. 4