Reduction of antibiotics using microorganisms containing glutathione S-transferases under immobilized conditions
Reduction of antibiotics using microorganisms containing glutathione S-transferases under immobilized conditions
复制标题
DOI：
10.1016/j.etap.2012.05.011
复制
发表时间：
2012-09-01
影响因子：
4.3
通讯作者：
Park, Hyeyoung
中科院分区：
文献类型：
--
作者：
Park, Hyeyoung
用含有谷胱甘肽s -转移酶（GSTs）的固定化细菌细胞降解几种抗生素（四环素、磺胺噻唑、氨苄西林）。动物饲料污染废水中的抗生素通常会抑制处理废水的微生物的生长，因此需要一种生物友好的处理方法。因此，我们已经证明，在生物反应器中使用细胞固定化方法，含有解毒酶GSTs的微生物可以降低抗生素对细菌的抑制作用。四环素、磺胺噻唑和氨苄西林的初始浓度分别为100 mg/L、100 mg/L和50 mg/L，是韩国猪饲料中典型的检测范围。在实验结果中，我们观察到生物反应器中四环素对表皮葡萄球菌的去除率接近70%，表明这种抗生素去除方法值得进一步研究。(C) 2012 Elsevier B.V.版权所有
The degradation of several antibiotics (tetracycline, sulfathiazole, ampicillin) was performed with immobilized bacterial cells containing the glutathione S-transferases (GSTs). Antibiotics in animal feed contaminated wastewater usually inhibit the growth of microorganisms that treat the wastewater, so a bio-friendly treatment method is required. Therefore, we have shown that the inhibitory effects of antibiotics on bacteria were reduced by microorganisms containing detoxifying enzyme GSTs by using a cell immobilizing method in a bioreactor. The initial concentrations of tetracycline, sulfathiazole and ampicillin were 100 mg/L, 100 mg/L and 50 mg/L respectively, which are typical of the range detected in pig feed in Korea. In the results, we observed the removal efficiency of tetracycline to be almost 70% with Staphylococcus epidermidis in the bioreactor, suggesting that this method of antibiotic removal is worthy of further study. (C) 2012 Elsevier B.V. All rights reserved.