Childhood obsessive-compulsive personality traits' in adult women with eating disorders: Defining a broader eating disorder phenotype
Childhood obsessive-compulsive personality traits' in adult women with eating disorders: Defining a broader eating disorder phenotype
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DOI：
10.1176/appi.ajp.160.2.242
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发表时间：
2003-02-01
影响因子：
17.7
通讯作者：
Treasure, J
中科院分区：
文献类型：
--
作者：
Anderluh, MB;Tchanturia, K;Treasure, J
目的：作者回顾性研究了反映患有饮食失调的成年女性强迫症人格的童年特征，并评估了这些特征对饮食失调发展的预测价值。方法：采用病例对照设计，对44名神经性厌食症女性、28名神经性贪食症女性和28名健康女性受试者进行访谈，要求她们回忆是否经历过与强迫症人格相关的各种类型的童年行为。的。受试者还完成了强迫症（OCD）症状的自我报告清单。结果：儿童强迫性人格特征对饮食失调的发展具有很高的预测价值，每增加一个特征，饮食失调的比值比就会增加6.9倍。与没有报告这些特征的饮食失调患者相比，在童年时期表现出完美主义和僵化的饮食失调患者在以后的生活中出现强迫症和强迫症共病的几率要高得多。结论：反映强迫症人格的童年特征似乎是饮食失调发展的重要危险因素，可能代表神经性厌食症患者特定亚组更广泛表型的标志。
Objective: The authors retrospectively examined a spectrum of childhood traits that reflect obsessive-compulsive personality in adult women with eating disorders and assessed the predictive value of the traits for the development of eating disorders.Method: In a case-control design, 44 women with anorexia nervosa, 28 women with bulimia nervosa, and 28 healthy female comparison subjects were assessed with an interview instrument that asked them to recall whether they had experienced various types of childhood behavior suggesting traits associated with obsessive-compulsive personality. The. subjects also completed a self-report inventory of obsessive-compulsive disorder (OCD) symptoms.Results: Childhood obsessive-compulsive personality traits showed a high predictive value for development of eating disorders, with the estimated odds ratio for eating disorders increasing by a factor of 6.9 for every additional trait present. Subjects with eating disorders who reported perfectionism and rigidity in childhood had significantly higher rates of obsessive-compulsive personality disorder and OCD comorbidity later in life, compared with eating disorder subjects who did not report those traits.Conclusions: Childhood traits reflecting obsessive-compulsive personality appear to be important risk factors for the development of eating disorders and may represent markers of a broader phenotype for a specific subgroup of patients with anorexia nervosa.