Nanocellulose-Mediated Electroconductive Self-Healing Hydrogels with High Strength, Plasticity, Viscoelasticity, Stretchability, and Biocompatibility toward Multifunctional Applications
Nanocellulose-Mediated Electroconductive Self-Healing Hydrogels with High Strength, Plasticity, Viscoelasticity, Stretchability, and Biocompatibility toward Multifunctional Applications
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纳米纤维素介导的导电自修复水凝胶具有高强度、可塑性、粘弹性、拉伸性和生物相容性，可用于多功能应用
DOI：
10.1021/acsami.8b09656
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发表时间：
2018-08-22
影响因子：
9.5
通讯作者：
Han, Jingquan
中科院分区：
文献类型：
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作者：
Ding, Qinqin;Xu, Xinwu;Han, Jingquan
导电聚合物水凝胶（CPH）已成为一类迷人的智能软物质，对各种先进的应用很重要。然而，实现导电性、自愈合能力、生物相容性、粘弹性和高机械性能的协同特性仍然是一个关键的挑战。在这里，我们首次开发了一种基于粘弹性聚乙烯醇（PVA）-聚乙烯醇（PB）凝胶基质和纳米结构CNFs-PPy（纤维素纳米纤维聚吡咯）复合物的多功能混合CPHs，该复合物协同CNFs的生物模板作用和PPy的导电性质。通过在CNF模板表面原位氧化聚合吡咯，合成了CNF-PPy复合物，并将其分散到PB基体中，制备了均匀的CNF-PPy/ PB杂化水凝胶。CNF-PPy复合物不仅通过氢键与PVA分子链缠结在一起，而且与硼酸根离子形成可逆交联复合物。各组分之间的多重复合作用导致形成层次化的三维网络。当PVA2.0wt%、PEG0.4wt%、CNF-PPy复合物质量比为3.75/1时，制备的CNF-PPy/PB-3水凝胶具有最高的粘弹性和机械强度。由于水凝胶内部的组合增强和导电网络，其最大储能模量（类似于0.1MPa）和标称压缩应力（类似于22 MPa）分别是纯CNF/PB水凝胶的60倍和2240倍。电导率为3.65 ± 0.08 S m（-1）的CNF-PPy/PB-3电极的最大比电容为236.9 F g（-1），循环1500次后比电容衰减小于14%。CNF-PPy/PB杂化水凝胶还表现出有吸引力的特性，包括高含水量（类似于94%）、低密度（类似于1.2 g cm（-3））、优异的生物相容性、可塑性、pH敏感性和快速自愈合能力而无需额外的外部刺激。总之，这种独特的性质的组合赋予了新开发的CPH在柔性生物电子学中的潜在应用，并为设计多功能智能软材料提供了实用平台。
Conducting polymer hydrogels (CPHs) have emerged as a fascinating class of smart soft matters important for various advanced applications. However, achieving the synergistic characteristics of conductivity, self-healing ability, biocompatibility, viscoelasticity, and high mechanical performance still remains a critical challenge. Here, we develop for the first time a type of multifunctional hybrid CPHs based on a viscoelastic polyvinyl alcohol (PVA)-borax (PB) gel matrix and nanostructured CNFs-PPy (cellulose nanofiberspolypyrrole) complexes that synergizes the biotemplate role of CNFs and the conductive nature of PPy. The CNF-PPy complexes are synthesized through in situ oxidative polymerization of pyrrole on the surface of CNF templates, which are further well-dispersed into the PB matrix to synthesize homogeneous CNF-PPy/ PB hybrid hydrogels. The CNF-PPy complexes not only tangle with PVA chains though hydrogen bonds, but also form reversibly cross-linked complexes with borate ions. The multi-complexation between each component leads to the formation of a hierarchical three-dimensional network. The CNF-PPy/PB-3 hydrogel prepared by 2.0 wt % of PVA, 0.4 wt % of borax, and CNF-PPy complexes with a mass ratio of 3.75/1 exhibits the highest viscoelasticity and mechanical strength. Because of a combined reinforcing and conductive network inside the hydrogel, its maximum storage modulus (similar to 0.1 MPa) and nominal compression stress (similar to 22 MPa) are 60 and 2240 times higher than those of pure CNF/PB hydrogel, respectively. The CNF-PPy/PB-3 electrode with a conductivity of 3.65 +/- 0.08 S m(-1) has a maximum specific capacitance of 236.9 F g(-1), and its specific capacitance degradation is less than 14% after 1500 cycles. The CNF-PPy/PB hybrid hydrogels also demonstrate attractive characteristics, including high water content (similar to 94%), low density (similar to 1.2 g cm(-3)), excellent biocompatibility, plasticity, pH sensitivity, and rapid self-healing ability without additional external stimuli. Taken together, the combination of such unique properties endows the newly developed CPHs with potential applications in flexible bioelectronics and provides a practical platform to design multifunctional smart soft materials.